Question | Answer |
The erythrocyte stage that marks the beginning of hemoglobinization is called: | Polychromatophilic normoblast |
The red cell protein that is responsible for deformability and flexibility of the red cell is: | Spectrin |
What is the RBC pathways is responsible for providing 90% of the cellular AATP for red cell metabolism? | Embden-Meyerhof pathway |
The basic pathophysiology of the thalassemic conditions is a: | Decreased or absent globin chain synthesis |
Polychromatophilic macrocytes in the peripheral smear are most likely: | Reticulocytes |
The degree of effective erythropoietic activity in any hematological disorder is most readily assessed by a: | Reticulocyte count |
Most hypochromic cells will have an MCHC that is: | Less than 30% |
The last nucleated stage of erythrocytic maturation is the: | Orthochromic normoblast |
From each pronormoblast precursor cell, ____ mature red blood cells are produced. | 16 |
The higher the N:C ratio, the more mature the cell. | False |
One of the key morphological features of the nucleated red cell stages is: | A round nucleus |
Increased plasma cholesterol may lead to the development of which of these abnormal red cell morphologies? | Target cells |
The hemoglobin molecule consists of: | four heme molecules, four globin chains |
Asynchrony in the bone marrow is defined as the: | Nuclear development and hemoglobin development that is unbalanced |
The red cell inclusion derived from denatured hemoglobin are: | Heinz bodies |
When hemolysis is produced by the intravascular fragmentation of red cells, which red cell morphology will be produced? | Schistocytes |
Red cell inclusions that are remnants of DNA are termed: | Howell Jolly bodies |
Pappenheimer bodies are composed of: | Iron |
Reversible sickled cells are described as having a: | Half-moon shape with rounded ends |
The anucleate mature red blood cell has no ability to produce protein. | True |
What is a significant morphologic difference between irreversibly sickled cells and reversible sickled cells? | Pointed projections to the sickle cell |
What are two integral proteins in the red blood cell structure that house red blood cell antigens? | Glycophorin A and glycophorin B |
All are characteristic of the red blood cell in stages of development: | nuclei are "baseball round", immature cells are larger, N:C ratio decreases as the cell matures |
A characteristic that is not a stage of development of the red blood cell: | distinct granulation in the cytoplasm |
What red blood cell inclusions originate as a result of denatured hemoglobin? | Heinz bodies |
In which conditions can you see elliptocytes? | Iron deficiency anemia |
What red blood cell morphology may form as a result of excess cholesterol taken on the red blood cell membrane? | Target cells |
Hypochromia is used to define: | Decrease in hemoglobin content of the red blood cell |
The erythrocyte stage that marks the beginning of hemoglobinization is called: | Polychromatophilic normoblast |
A key morphologic feature of the nucleated red blood cell stages is : | "Baseball" round nucleus |
The red blood cell protein that is responsible for deformability and flexibility of the red blood cell is: | Spectrin |