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Hematology 1
Hematology in Practice - Chapter 3
| Question | Answer |
|---|---|
| The erythrocyte stage that marks the beginning of hemoglobinization is called: | Polychromatophilic normoblast |
| The red cell protein that is responsible for deformability and flexibility of the red cell is: | Spectrin |
| What is the RBC pathways is responsible for providing 90% of the cellular AATP for red cell metabolism? | Embden-Meyerhof pathway |
| The basic pathophysiology of the thalassemic conditions is a: | Decreased or absent globin chain synthesis |
| Polychromatophilic macrocytes in the peripheral smear are most likely: | Reticulocytes |
| The degree of effective erythropoietic activity in any hematological disorder is most readily assessed by a: | Reticulocyte count |
| Most hypochromic cells will have an MCHC that is: | Less than 30% |
| The last nucleated stage of erythrocytic maturation is the: | Orthochromic normoblast |
| From each pronormoblast precursor cell, ____ mature red blood cells are produced. | 16 |
| The higher the N:C ratio, the more mature the cell. | False |
| One of the key morphological features of the nucleated red cell stages is: | A round nucleus |
| Increased plasma cholesterol may lead to the development of which of these abnormal red cell morphologies? | Target cells |
| The hemoglobin molecule consists of: | four heme molecules, four globin chains |
| Asynchrony in the bone marrow is defined as the: | Nuclear development and hemoglobin development that is unbalanced |
| The red cell inclusion derived from denatured hemoglobin are: | Heinz bodies |
| When hemolysis is produced by the intravascular fragmentation of red cells, which red cell morphology will be produced? | Schistocytes |
| Red cell inclusions that are remnants of DNA are termed: | Howell Jolly bodies |
| Pappenheimer bodies are composed of: | Iron |
| Reversible sickled cells are described as having a: | Half-moon shape with rounded ends |
| The anucleate mature red blood cell has no ability to produce protein. | True |
| What is a significant morphologic difference between irreversibly sickled cells and reversible sickled cells? | Pointed projections to the sickle cell |
| What are two integral proteins in the red blood cell structure that house red blood cell antigens? | Glycophorin A and glycophorin B |
| All are characteristic of the red blood cell in stages of development: | nuclei are "baseball round", immature cells are larger, N:C ratio decreases as the cell matures |
| A characteristic that is not a stage of development of the red blood cell: | distinct granulation in the cytoplasm |
| What red blood cell inclusions originate as a result of denatured hemoglobin? | Heinz bodies |
| In which conditions can you see elliptocytes? | Iron deficiency anemia |
| What red blood cell morphology may form as a result of excess cholesterol taken on the red blood cell membrane? | Target cells |
| Hypochromia is used to define: | Decrease in hemoglobin content of the red blood cell |
| The erythrocyte stage that marks the beginning of hemoglobinization is called: | Polychromatophilic normoblast |
| A key morphologic feature of the nucleated red blood cell stages is : | "Baseball" round nucleus |
| The red blood cell protein that is responsible for deformability and flexibility of the red blood cell is: | Spectrin |
Created by:
Megan Hohenberg
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