Question | Answer |
Discovery of first Rh antigen | Levine and Stetson. |
Rh is named after | Rhesus monkeys |
Genes for ABO antigens are located on | Chromosome #9 |
Genes for D antigen are located on | Chromosome #1 |
What is a Rh Control? | identical to anti-D sera but not antibody. |
Weak D testing includes | incubating 37 degrees C for 15 to 60 minutes. Cells are washed 3-4 times |
What is Rogam | rh immune globulin to prevent rh neg individuals who are exposed to rh positive RBC from developing Anti-D |
Discovery of first Rh antigen | Levine and Stetson. |
Rh is named after | Rhesus monkeys |
Genes for ABO antigens are located on | Chromosome #9 |
Genes for D antigen are located on | Chromosome #1 |
What is a Rh Control? | identical to anti-D sera but not antibody. |
Weak D testing includes | incubating 37 degrees C for 15 to 60 minutes. Cells are washed 3-4 times |
What is Rogam | rh immune globulin to prevent rh neg individuals who are exposed to rh positive RBC from developing Anti-D |
What is 25% albumin used for | reduces zeta potential. allowing rbc to approach each other |
What does PEG do (polyethylene Glycol) | removes water from test. Most sensitive and most false positives results. |
Agglutination or Hemolysis at any stage of antibody screen | is a positive result. |
Most common cold antibodies | anti- N, anti-P and anti I
IgM immediate spin |
Most common warm antibodies | Rh,Kell, Kidd, Duffy |
What does it mean if you have a positive auto control? | suggest autoantibody or medication antibody. Usually Lea or Leb |
What are the dosage antibodies | kidd,dffy,Rh,MNs
Kidds and Duffy the monkey eat M&N |
Lewis system | antigen made in tissue and secreted into blood. Inheritance depends on both genes and secretor genes. |
Only in childhood can show this lewis pattern | Le(a+b-) or Le (a+b+) |
What is the related disease state with Lewis antigens | peptic ulcers and H.Pylori
Tumor formation, transplant failures |
I Blood system (individuality), at birth is?
In adults? | rich in i as infant
rich in I as adult |
Production of Autoanti-I are associated with what disease states? | Mycopasma pnumoniae and monucleosis |
M and N antiges are found on | glycoprotein A |
S and S antiges are found on | glycoprotein B |
Anti- M is associated with | Burn patients of bacterial infections |
Cold antibodies (naturally occuring ) are | LiPMAN |
K | Kell |
k | cellano |
KPa | penny |
KPb | ratenberg |
Kell is associate with which syndrome | McLeod -muscle and nerve, slow from of muscular distrophy. acanthrocyte prodction. |
Fy(a-b-) null phenotype- common in blacks in africa can resist | plasmodium |
Kidd antibodies are common in | HTR |
Diego is higher in | Asians and South American populations |
Diego is useful in | mongolian ancestry research |