Question | Answer |
autosomal disorder with large lysosomal inclusions, recurring infections, and albinism | Chediak-higashi sydrome |
Initial appearance of specific granulation in the granulocytic series is predominantly seen in: | myelocyte |
All of the following are mechanisms by which neutropenia is usually produced by | viral infection (not bacterial) |
The marginating pool of neutrophil is located | vessel endothelium in the bone marrow |
The monoclonal marker that is often positive in T-ALL (Acute Lymphoblastic Leukimia) is | positive CD7 and CD3 |
Causes of secondary erythrocytosis | Hypertension, arterial hypoxemia, drugs, smoking, alcohol, renal disease, renal lesions, endocrine lesions, hepatic lesions, impaired oxygen delivary |
Myocardial infractions, transient ischemic attacks, and deep vein thrombosis are more likely to be complications of | (PV) Polycytemia Vera |
One of the primary glands in the infant responsible for lymphocyte origination is the | thymus |
Osponization of neutrophils is defined as | Stage 2: Attaching to foreign bodies preparing them to be ingested |
Tyrosine kinanse is an important mediator in leukocyte metabolic pathways because it suppresses | apoptosis (natural cell death) |
The red cell morphology that is associated with MMM (myloproliferative Myeloid Metaplasia | teardrop, nRBC |
Acute leukemia is characterized by | Blasts - myeloblast over > 20% |
A patient with AML (Acute Myeloid Leukemia)is likely to have a cytochemical panel that is positive for | MPO (myeloperoxidase), SSB (sudan Black B), CAE (chloroacetate esterase), NSE (non specific esterase |
Which CD markers are appropriately associated with the meylocyte | CD45, CD33, CD13 |
Which CD marker best represents the earliest progenitor cells | CD34 (TdT, HCA-DR) |
The accelerated phase of chronic myeloid leukemia is marked by | basophil > 20% |
A "dry tap" is a characteristic of myeloid fibrosis with myeloid metaplasia due to | Inability to obtain a spinal tap sample due to the architecture of the bone marrow is disrupted by fibrotic tissue (reticulin) |
Pure erythroid leukemia is defined as | most marrow cells > 80% comprising of erythroid precursors, w/out myeloid proliferation |
What effect does the Ph chromosome t(9:22) have on the prognosis of patients with chronic myelocytic leukemia | better prognosis, lacking Ph 1 median survival is 1 yr |
The best corrective action to take for a patient who exhibits platelet satellitism in the peripheral blood smear is to | collect in sodium citrate tube |
The LAP (cytochemical stain) is helpful in distinguishing | CML or CGL (Chronic Myelocyte/Granular Leukemia)from Leukemoid reaction. (LAP enzyme is in the granules of neutrophils) |
The t(15:17) (q22:q12) is associated with what leukemia(s): | APL (Acute Promyelocitic Leukemia) |
A high risk factor for the diagnosis of essential thromocythemia is | Increased platelet count (>600), age, previous thrombotic event |
A patient who has persistent leukocytosis, Dohle bodies, and an elevated LAP score most likely has | Leukemoid reaction |
Describe Auer rods | Elliptical, spindle like inclusions composed of azurophilic granules that may be present in Myeloblast, monoblast, or promyelocytes in AML |
A term describing a periphreal blood finding of leukocytosis with a shift to the left accompanied by occasional nRBC's and platelet abnormalities is | Leukoerythroblastosis |
A white cell disorder that presents with a low
WBC count, thrombocytopenia, and a mulberry like inclusion in the monocytes is | (HE) Human Erlichiosis (*He goes round the mulberry bush) |
Name all the features of the lymphatic system | Blood filtration, fluid balance, antibody generation, lymphoporesis |
Define delta check | Comparing lab results with patients history of lab results |