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Pain Physiology
Reception, Propagation
Question | Answer |
---|---|
What are the 2 types of Pain Receptors? | Mecanothermal, Chemosensitive Nociceptors |
What triggers a Mechanothermal Nociceptor response? | Intense/Severe MECHANICAL stimuli, TEMPERATURE extremes |
What is an example of a Mecanothermal Nociceptor Stimulus? | Pinch |
What triggers a Chemosensitive Nociceptor response? | Major Truama --> releases Bradykinin, Histamine, Prostaglandins from injured cells |
What is an example of a Chemosensitive Nociceptor Stimulus? | major Infection, Disease, severe Burns - Cell Death |
Why do 3rd degree burns have less pain that 1st or 2nd degree burns? | deep tissue burns damage Chemosensitive Nociceptors |
Were do A-fibers come from? | from Mechanothermal Nociceptors |
What are 3 characteristics of A-fibers? | 1. THICK well-myelinated; 2. FAST conduction velocity; 3. 1st PAIN |
Describe 1st Pain. | Short, Sharp, Stinging, Well-Localized |
Where does 1st pain occur? | propagated from SKIN only |
What are 3 characteristics of C-fibers? | 1. THIN poorly-myelinated; 2. SLOW conduction velocity; 3. 2nd PAIN |
Describe 2nd Pain. | Long-Lasting, Burning |
Where does 2nd Pain occur? | propagated from Skin, Deep Tissues, Organs |
What is the significance of A-fibers? | responds to lower levels of injury - Early Warning, take evasive action |
Wat is the significance of C-fibers? | incapacitating pain - prevents further injury |