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Physiology I
Blood Groups - Test 2
| Question | Answer |
|---|---|
| What are the types of immune reactions of blood? | 1. Reactions caused by antigenicity 2. Antigens on Cell Membranes 3. Antibodies in plasma 4. Transfusion reactions |
| Agglutinogens are also known as? | Antigens |
| What type of Antigen is found with all ABO blood types? | H Antigen |
| What is Bombay phenotype? | Persons containing no ABO blood group antigens |
| What blood type has no A or B antigen? | Type O |
| True or False, A and B are dominant? | True |
| True or False, Type O is recessive? | True |
| Define genotype? | The actual genes received from parents |
| Define phenotype? | How the genes are expressed. |
| How many antibodies are you born with? | 0 |
| Anitbodies begin to develope at the age of ____ to 8 months? | 2 to 8 months |
| At what age do you have the most antibodeis present? | 8-10 years of age |
| Agglutinins are fomed from? | Gamma Globulins - mostly IgM and IgG |
| What are the two types of Blood Typing? | 1. Forward Typing 2. Reverse Typing |
| What are the 6 types of Rh antigens? | D,C,E, d,c,e |
| Which Rh antigens are dominant? | D,C,E |
| Which Rh antigens are recessive? | d,c,e |
| What is the diffenrence in Rh- and Rh+? | Rh+ has D antigen, Rh- does not have D antigen |
| Which Rh antigen is the most antigenic? | D |
| What is erythroblastosis fetalis? | A hemolytic disease in newborns that is characterized by agglutination and phagocytosis of the RBC's. (Rh- mother and Rh+ baby) |
| What does kernicterus cause? | 1. Jaundice 2. Mental Retardation 3. Death |
| What are the 4 types of tissue grafts? | 1. Autograft - transplant from and into the same animal 2. Isograft - Graft from identical twin 3. Allograft - Graft from same species 4. Xenograft - Graft from different species |
| What is the importnace of the HLA complex? | The HLA Complex is the most important antigens for causing graft rejection |
| How many HLA complexes are present on the cell surface of any one person? | Only 6, but there are 150 different types that creates a trillion different combinations. |
| How is graft rejection prevented? | By suppressing the Immune sytem - especially T-Cells and using Glucocorticoid hormones, cylcosporine, and other drugs that are toxic to lymphoid tissue |
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Tri 2
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