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Action Potentials


What is the definition of Threshold Stimulation? the minimum DEPOLARIZATION required to trigger a Na+ permeability change --> AP
What is the definitions of Subthreshold? Insufficient DEPOLARIAZATION for a response
T/F The lower the amplitude of an AP the less likely it is to reach the synapse. F. All-or-None Principle - AP attains FULL amplitude (30mv at 1ms) or it does not occur
What is Hyperpolarization? MORE negative RP --> decreased membrane excitability
What are some of the causes of Hyperpolarization? 1. INTERFERENCE with Na+ INFLUX; 2. INCREASED Extracellular Ca++
What medicine causes Hyperpolarization and what is its function? Lidocaine - interference with Na+ INFLUX - anesthesia
What is Depolarization? LESS negative RP --> INCREASED membrane Excitability
What are some causes of Depolarization? 1. ENHANCEMENT of Na+ INFLUX; 2. DECREASED Extracellular Ca++
What is Paresthesia? Increased membrane permeability
What is a side effect of Paresthesia? Abnormal Sensation, Hallucination, Hearing Things, Schizo
Created by: Kristel