Save
Busy. Please wait.
Log in with Clever
or
show password
Forgot Password?
Don't have an account?  Sign up 
Sign up using Clever
or
Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account. Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't Know
Remaining cards (0)
Know
0:00
edit
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Phys3 K+ balance

QuestionAnswer
Where does Medullary K+ recycling occur? Long looped juxtaglomerular nephrons.
Steps of medullary K+ recycling 1.K+ secreted into thin descending limb. 2.K+ is reabsorbed by both ascending limbs & deposits in the interstitium. 3.K+ is reabsorbed from medullary CDs and deposits in interstitium. 4.K+ becomes trapped in medullar interstitium.
What is the net movement of K+ in the loop of Henle? REABSORPTION. ascending loops reabsorb more than descending loops secrete.
Where is interstitial K+ highest? At the papilla.
Why is the high medullary [K+] created from K+ recycling important? During high K+ intake, there is a lot of secretion into the tubule lumen (as high as 200mOsm). With a high interstitial [K+], there will be less passive diffusion out of the tubule lumen.
What type of reabsorption of K+ occurs in the PT? paracellular.
How is K+ reabsorbed in the thick ascending limb? Via NKCC (Na/2CL/K symporters) which are the target of loop diuretics.
How do principle cells effect [K+] They secrete K+ through channels on the apical membrane into the tubule lumen.
How do loop diuretics affecting the PT, Loop of Henle, and DCT affect [K+] 1.Inhibit K reabsorption. 2.Inc K secretion. **INCREASE K+ EXCRETION.
Types of K+ channels on apical principal cell membrane and how they respond to [K+] 2 types: ROMK & BK. 1.Low [K+]: ROMK sequestered, BK closed. 2.Normal [K+]: ROMK open, BK closed. 3.High [K+]: Both are OPEN. **respond to K+ excretory rate.
When are principle BK channels on the apical membrane open? Hyperkalemia.
What occurs on the apicl membrane of the CDs to affect [K+] REASBSORPTION through H/K exchangers.
Factors causing Inc K+ secretion in distal nephron 1.High K diet. 2.Non-Chloride anions in distal nephron. 3.High flow rate in distal nephron. 4.High Na delivery in distal nephron. 5.High plasma K. **Hyperkalemia will trigger aldosterone.
Metabolic acidosis' affect on K+ H+ wants to move out of the plasma and into the cell to restore pH. This causes K+ to move into plasma: HYPERKALEMIA.
Metabolic alkalosis' affect on K+ H+ wants to move into the plasma to restore pH. Therefore K+ moves out into the cells causing: HYPOKALEMIA
Created by: WeeG
Popular Physiology sets

 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!
"Know" box contains:
Time elapsed:
Retries:
restart all cards