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Test 1 RX1020 Review
Question | Answer |
---|---|
Drugs that are derived from natural sources are known as what? | Natural drugs |
Drugs that are produced in the laboratory and are not naturally occurring are known as what? | Synthetic drugs |
A naturally occurring substance that has been chemically altered is known as what typw of drug? | Semi-synthetic |
A drug that is made in a laboratory to imitate a drug that is naturally occurring is known as what? | Synthesized |
Drugs that are synthetic and produced by means of recombinant DNA or Mabs are known as what? | Monochional antibodies |
A set of names: way of naming is known as what? | nomenclature |
The registered name of a drug; also known as the proprietary name? | Trade or brand name |
The extremely lengthy name of the drug that is difficult to remember or pronounce is known as what? | Chemical name |
The shorter names used to identify a drug's active ingredient; also referred to as the nonproprietary name? | generic name |
The actual form of the drug is known as what? | dosage form |
What are the two primary dosage preparations? | liquid and solid |
The most widely available dosage form is what? | solid |
Name 3 of the disadvantages of solid medications? | 1. difficult for patient to swallow 2. not for patients what are unconscious/breathing tubes. 3. medication can be destroyed by the digestion process. |
The other ingredients, besides the active drug, in a drug form are known as what? | inactive or inert |
What is the purpose of a film coating on a tablet? | make tabley easy to swallow |
What is the purpose of an enteric coating on a tablet? | stop tablet from being dissolved by the gastric acids in the stomach |
List and explain the 5 types of tablets? NOT swallowed | 1. CHEWABLE-not take whole used for pediatrics and elderly. chew it2. EFFERVESCENT-dissolves in liquid before administered. 3.SUBLINGUAL-under tonguw,4.BUCCAL cheek & gum5.VAGINAL-absorb mucous lining of vaginal. |
A solid medication form in which the ingredients of a drug are contained within a shell is known as what? | capsules |
What are most capsule shells made out of? | gelatin |
The fluid medium of a liquid medication is called what? | vehicle |
Containing oil; having oil like properties? give vocab word | Oleginous |
Containing what? Give the vocab word | Aqueous-contains water |
List 3 disadvantages of liquid medications. | 1. shorter life than other doses 2. some have a bad taste3. harder for patients to measured. |
Medication that is completely dissolved and evenly distributed in a homogenous mixture is known as what? | solutions |
Define Homogenous | having all the same qualities in a group |
Define Viscous | thick almost jelly-like |
What is the agent used to mix oil and water elements in an emulsion? | emulsifying agent |
Liquid dosage form where very fine solid particles are mixed into a liquid vehicle is lnown as what? | suspentions |
What are the differences between ointments,creams, & lotions? | OINTMENT apply to skin(mucus membrane)lubricate skin,protect sking,w/wo med.CREAMS-lighter than otmnts.apply easy-cool,dry,protect skinw/womed.LOTIONS-moisturizes skin..... |
Define Anhydrous | without water |
Define Hydrophobic | repels water |
How a drug is introduced into or on the body is known as what? | ROA Route of Administration |
Main category of administration routes where the medication passes through the GI system is known as what? | Enteral |
Most common ROA is what? | oral by mouth |
What is another name for the transdermal route of administration? | percutaneous |
The shallowest injectable ROA; into the top layer of skin is known as what? | Intradermal |
The injectable ROA where the medication os injected into the fatty tissue immediately under the skin is known as what? | subcutaneous SC/SQ |
The injectable ROA administered directly into the vein is known as what? | intravenous IV |
Define Otic ROA | medication administered to the ear |
The study of the biochemical and physiologic effects of a drug is known as what? | Pharmacodynamics |
Molecular structures located on the surface of the cell that binds with a particular chemical or chemicals are known as what? | receptors |
Describe how drugs and receptor sites interact | like a lock and key |
The location where a drug will exert its effect is known as what? | site of action |
How a drug works and produces its effects is known as whaat? | mechanism of action |
A drug that binds to receptor sites and causes some action to occur is known as what? | agonist |
A drug that binds to receptor sites and prevents other chemicals or drugs from affecting the cell is known as what? | antagonist |
A general term referring to a large number of cells on what a particular drug is intended to act is what? | target cell |
Patient response that is directly related to the amount of the drug administered in known as what? | dose response curve |
What happens if the maximal response is attained and more of the same drug is given | have no effect |
The area where therapeutic effect can be achieved without toxicity is known as what? | margin of safety |
The amount of circulating drug that causes toxicity is known as what? | toxic concentration |
The measurement of the strength of a drug that is required to produce a specific effect on the body is known as what? | potency |
The time required for plasma serum concentration levels of an absorbed and distributed drug to decrease by one-half is known as what? | biological half-life |
Half life is only applicable to what types of drugs? | drug that goes thru liver as well as GI tract |
How is half-life written | T1/2 |
An interaction that occurs between 2 or more drugs administered at the same time is known as what? | drug-drug |
AN interaction between an administered drug and food(s) consumed at the same time is known as what? | drug-food |
A drug interaction that results when 2 drugs administered together produce effects that are greater than would be produced if either drug were administered alone is known as what? | synergistic effects |
A drug interaction that results when 1 drug,or good, increases the effects of another drug yet does not produce any effect when administered alone is known as what? | potentiation |
A drug interaction that causes decreased drug effects is known as what? | antagonism |
The study of the time course of a drug and its metabolites in the body following drug administration is known as what? | pharmacokinetics |
The process by which a drug is moved from the site of administration into the bloodstream is known as what? | absorption |
Oral medications are normally absorbed through which organism? | small intestines |
The process by which an absorbed drig is moved from the bloodstream to body tissues or receptors is known as what? | distribution |
What type of diffusion has molecules moving from an area with a high concentration to an area of low concentration? | passive diffusion |
What type of diffusion uses a carrier protein to allow molecules to pass through parts of a cell? | carrier protein |
The process where the cell actually grabs or engulfs the outside substance is referred to as what? | pinocytosis |
What is the degree to which a drug becomes available to body tissues after administration known as? | bioavailability |
The ability of the stomach to allow passage of materials to the small intestines is known as what? | gastric emptying time |
The ability of a material to dissolve in a given medium is known as what? | solubility |
Lipid soluable drugs dissolve in the presence of what? | fats (lipids) |
Water soluable drugs dissolve in the presence of what? | water |
The process of transforming drugs in the body is known as what? | metabolism |
Where are most drugs metabolized | liver |
Any substance that is produced by the metabolic process is known as what? | metabolite |
The process by which drugs are eliminated from the body is known as what? | excretion |
The time it takes for a drug to be eliminated from the body is known as what? | clearance |
Most medications are excreted as that substance? | urine |
Most medications go through which organ for excretion? | kidneys |
Drugs that become active once metabolized are known as what? | prodrugs |