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Phys Lect 21
| Question | Answer |
|---|---|
| Response to spinal cord denervation: Can Parasymp/symp response return to an organ after innervation has been cut? | Yes, over time, the organ will increase its sensitivity to the neurotransmitter by increasing the number of receptors (Upregulation). **pupil dilation will return after sup cervical ganglionectomy |
| How do Parasymp and symp preganglionic cells differ in their postganglionic synapses | Parasymp: Pregang synapse with FEW postgang cells. Symp: Pregang synapse with MANY postgang (also has a bigger response due to chromaffin cells) |
| Function of Alpha 2 adrenergic receptors in BOTH symp and Parasymp | A2 receptors are located on the presynaptic neuron axon terminal membrane. NE/E binds and causes inhibitory response (Cl- influx or K+ efflux). This makes the symp signaling brief and turns off parasymp when symp are very active. |
| What type of process is Vasodilation? | PASSIVE. it is a decrease in sympathetic tone (firing) to the BL vessels. **Less than the normal resting tone. |
| What happens to the BL vessels if there is an increased sympathetic tone/ firing rate | Vasoconstriction. **Unless there is a higher density of B2 receptors and Epi has been released in the BL by the chromaffin cells. |
| Referred pain: Erythema in response to gallbladder infection? | B/c the sensory afferents synapse at the same level as the symp cutaneous efferents (A2 rec), vasodilation can occur in the right upper quadrent due to increased inhibition of symp tone. **Also synapses with a motor neurons of abdominal muscles (Firmin |
| Hyperesthesia | Increased sensitivity to touch. Caused convergence of peripheral and abdominal afferents going to pain centers in brain |
| Hyperalgesia | Increased sensitivity to pain. Caused convergence of peripheral and abdominal afferents going to pain centers in brain |
| Main control centers in the Medulla Oblongata | 1.Circulatory Center. 2.Respiratory Center. |
| Main control centers in the Pons | 1.Micturition (INHIBITION 99% of time). |
| What is the central monitor of ANS? | Hypothalumus. Receives inputs from midbrain, CSF, and BL |