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Phys Lect 21

Response to spinal cord denervation: Can Parasymp/symp response return to an organ after innervation has been cut? Yes, over time, the organ will increase its sensitivity to the neurotransmitter by increasing the number of receptors (Upregulation). **pupil dilation will return after sup cervical ganglionectomy
How do Parasymp and symp preganglionic cells differ in their postganglionic synapses Parasymp: Pregang synapse with FEW postgang cells. Symp: Pregang synapse with MANY postgang (also has a bigger response due to chromaffin cells)
Function of Alpha 2 adrenergic receptors in BOTH symp and Parasymp A2 receptors are located on the presynaptic neuron axon terminal membrane. NE/E binds and causes inhibitory response (Cl- influx or K+ efflux). This makes the symp signaling brief and turns off parasymp when symp are very active.
What type of process is Vasodilation? PASSIVE. it is a decrease in sympathetic tone (firing) to the BL vessels. **Less than the normal resting tone.
What happens to the BL vessels if there is an increased sympathetic tone/ firing rate Vasoconstriction. **Unless there is a higher density of B2 receptors and Epi has been released in the BL by the chromaffin cells.
Referred pain: Erythema in response to gallbladder infection? B/c the sensory afferents synapse at the same level as the symp cutaneous efferents (A2 rec), vasodilation can occur in the right upper quadrent due to increased inhibition of symp tone. **Also synapses with a motor neurons of abdominal muscles (Firmin
Hyperesthesia Increased sensitivity to touch. Caused convergence of peripheral and abdominal afferents going to pain centers in brain
Hyperalgesia Increased sensitivity to pain. Caused convergence of peripheral and abdominal afferents going to pain centers in brain
Main control centers in the Medulla Oblongata 1.Circulatory Center. 2.Respiratory Center.
Main control centers in the Pons 1.Micturition (INHIBITION 99% of time).
What is the central monitor of ANS? Hypothalumus. Receives inputs from midbrain, CSF, and BL
Created by: WeeG