click below
click below
Normal Size Small Size show me how
DX Studies
Diagnostic Studies for Physician Assistants
Question | Answer |
---|---|
What are the indications for Amylase testing? | -Detect & monitor the course of pancreatitis (i.e. patient presents w/ LUQ tendernes) -Most sensitive test for pancreatitis -However, not specific for pancreatitis (bowel perf, peptic ulcer, duodenal obstruciton, mumps, renal failure, DKA) |
What is the clinical significance of Amylase? | Aids in catabolism of carbs. Secreted from acinar cells -> pancreatic duct -> duodenum. If pancreatic cells are damaged, this enzyme is released into the bloodstream. |
What can cause increased enzyme levels of Amylase? | -Damage to acinar cells (acute pancreatitis) -Obstruction of pancreatic duct flow (Pancreatic Ca, CBD stone) |
What is the time frame for Amylase levels? | Increased amylase level is apparent within 12 hours of acute pancreatitis. Returns to normal within 48-72 hours after onset of symptoms. However certain diseases can cause persistent elevated levels (i.e. pancreatic duct obstruction). |
What can cause decreased Amylase levels? | Chronic pancreatitis (pancreatic cell destruction) |
What are the indications for Lipase testing? | Evaluation of pancreatic disease |
What is the clinical significance of Lipase? | Secreted by pancreas into duodenum to break down triglycerides into fatty acids. Increased lipase levels occur with damage to or disease affecting pancreatic acinar cells. |
What is the time frame for Amylase levels? |