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EdemaCongHemInfarct
lecture 9 pinckard
Question | Answer |
---|---|
causes for edema | increased hydrostatic pressure, decreased osmotic pressure, lymphatic obstruction, Na/H2O retention, inflammation |
dependent edema | dependens on gravity, thus occurs in ext most often; most associated with CHF |
causes for anasarca | shock causing hypotension due to increased vascular hydraulic pressure or protein loss by kidneys in glomerular dz |
most common areas for brain herniation | cingulate gyrus below falx cerebri, cerebellar tonsils through foramen magnum, uncus through tentorium |
hyperemia vs congestion | hyperemia - active accumulation of blood due to increased flow, causes erythema congestion - accumulation of blood due to impaired venous return, causes hypoxia/cyanosis |
effects of left heart failure, gross and histologically | gross - dark, heavy and firm lungs histologically - macrophages full of hemosiderin after having eaten extravasated RBCs from chronic passive congestion, fibrotic alveolar septae |
effects of right heart failure, gross and histologically | gross - nutmeg liver with hemorrhagic areas histologically - congested vessels/residual RBCs not draining, fibrotic parenchyma |
organs with dual blood supply and/or loose parenchyma undergo this type of infarct | red - blood within infarct examples - bronchi, lungs, venous infarcts microscopically - coagulative necrosis gross - soft, red |
organs with only one blood supply and/or solid parenchyma undergo this type of infarct | white - no blood in infarct examples - heart, liver, spleen microscopically - coagulative necrosis gross - soft, white |
cause of septic infarcts | bacterial vegetation from heart valve breaks away and lodges somewhere as embolus, infarct eventually becomes an abscess |
time allows for ischemic/hypoxic tissue to develop collateral circulation and decrease risk of infarction |