Busy. Please wait.
Log in with Clever

show password
Forgot Password?

Don't have an account?  Sign up 
Sign up using Clever

Username is available taken
show password

Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Didn't know it?
click below
Knew it?
click below
Don't Know
Remaining cards (0)
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

TCA cycle

Per Westericks objectives

When does TCA occur (respiration) During aerobic respiration
What is the main regulatory enzyme of TCA cycle Isocitrate Dehydrogenase
Where does TCA occur Mitochondria
What are the starting materials of TCA cycle? Acetyl CoA, NAD+, FAD, GDP, and Pi
What are the products of TCA cycle? CO2, NADH, FADH2, GTP
What is the recycled 4 carbon compound of TCA cycle? Oxaloacaetate
Which dehydrogenase reduces FAD to FADH2 in TCA cycle? Succinate dehydrogenase
Which dehydrogneases reduce NAD+ to NADH in the TCA cycle? isocitrate dehydrogenase,aplha-ketoglutarate dehydrogenase, and malate dehydrgonenase
Why is TCA cycle completely aerobatic even though it does not use oxygen in cycle? The TCA cycle is aerobatic because it produces NADH which is oxidized in the OX-PHOS. OX-PHOS requires O2 and therefore if not O2 is avialible then OX-Phos doesnt occure. This results in a build up in NADH which inhibits TCA cycle and PDH.
What enzyme produces oxaloacetate from pyruvate? pyruvate carboxylase
How is Isocitrate dehydrogenase activated? ADP and CA2+ and isocitrate
If a patient is deficient in panthothenic acid, which cofactor of TCA will this affect? Co-enzyme A (CoA-SH)
If a patient is deficient in Niacin, which cofactor of TCA will this affect NAD+/NADH
If a patient is deficient in riboflavin, which cofactor of TCA will this affect? FAD/FADH2
If a patient is deficient in Thiamine pyrophospate (TPP), which cofactor of TCA will this affect? Thiamine
If a patient is deficient in Lipoic acid, which cofactor of TCA will this affect? lipomide
Pyruvate can be transaminated into which amino acid? alanine
Oxalacetate can be transaminated into which amino acid? aspartate
alpha-ketoglutarate can be transaminated into which amino acid? glutamate
What cofactors are required for alpha-ketoglutarate dehydrogenase? NAD+, thiamine pyrophosphate (PPT), and lipoic acid
What can oxaloacetate be converted to in order to cross the mitochondrial membrane? Malate or aspartate
What does the TCA cycle produce with amino acid carbons in the fed and fasted states? Fed states- CO2 and Fatty acids for triglycerides through citrate. Fasted state- carbon source for gluconeogensis as oxaloacetate.
How is TCA cycle connected to heme synthesis? Succinyl CoA leaves for heme snythesis in liver
How is TCA cycle connected to neurotransmitter synthesis? alpha-ketoglutarate leaves for glutamate and GABA snythesis
What is the rate limiting enzyme in the TCA cycle? isocitrate dehydrogenase
Created by: 721091545
Popular Biochemistry sets




Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!
"Know" box contains:
Time elapsed:
restart all cards