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pain neurophysiology

therapeutic mod pain neuro

Nerve Types Mylelinated, unmylelinated
Mylelinated Schwann cells form the myelin sheath around the axon of peripheral nerves Olgiodendrocytes form myelin sheath around the axons of the CNS NOR propagates the AP along the axon
Nodes of Ranvier increase speed of ocnduction only on mylelinated nerve cells propagate the AP along the axon
Unmylelinated No schawnn cells, olgiodendrocytes or NOR slower conduction velocities
Nerve classifications Efferent, Afferent
Efferent pathways Motor-A alpha EAT MOTOR NEURON DOES NOT INNERVATE THE SAME DUE TO THE FUNCTION(fine motor control has less then like back where the power is headed)
Motor unit alpha motor neuron and all the muscle fibers it innervates (efferent pathways)
Afferent Sensory-a beta, a delta,
What type of nerve fiber is the easiest to innervate large diameter fibers-have faster nerve conduction as well, A delta
A beta located in the skin sensitive to touch and vibration
A delta located in the skin sensitive to touch and vibration
C Muscle and skin sensetive to pain touch, pressure vibration and temperature
Resting membrane potential the voltage difference between the inside and outside of a cell (-60 to 90 mv) + charge on the outside of the cm due to increase Na - charge on the inside of the cm due to increased K+ Cl is in high concentration on the outside of CM
What maintains cell gradient and how? NA/K pump maintains cell gradient by pumping 3 Na out and 2K in which places a positive charge on the outside of the cell membrane
Resting Membrane Potential Depolarization, repolarization, hyperpolarization
Depolarization inside the cell becomes less negative
Repolarization cell membrane becoming more negative, closer to the RMP
Hyperpolarization cell membrain more negative than resting state
Action potential CM becomes permeable to a + charge causing a DP of the membrane,inside of the cell + to outside /\ in Na gradient then increases K gradient, a charge seperation across the membrane causes an AP to a + point K restores itself to a more - state causing
Absolute refractory period the basis of the absolute refractory period Na channels actually have 3 voltage gated configurations
Relative Refractory period Basis of the relative refractory period: The K+ over shoot K+ channels close near the RP Since the K+ changnels are slower, the membrane potential overshoots the RP about -80 mv near the K+
Na channels 3 volaged gated configurations Closed(at rest) Open(during AP) Inactive or refractor(just after an AP)
Closed configuration for NA channels ions cannot pass ready to open
Open configuration for Na channels Ions can pass through during an action potential
Inactive or refractory configuration of Na Channels ions cannot pass will not open
Created by: jwebst1