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Immunohematology MT

Module 2 - Rh

QuestionAnswer
Haplotype R1 is composed of what Gene locus(i) and antigens Loci: RHD, RHCe Antigens: D, C, e
Haplotype R2 is composed of what Gene locus(i) and antigens Loci: RHD, RHcE Antigens: D, c, E
Haplotype Rz is composed of what gene locus(i) and antigens loci: RHD, RHCE Antigens: D, C, E
Haplotype r' is composed of what gene locus(i) and antigens locus: RHCe Antigens: C, e
Haplotype r'' is composed of what gene locus(i) and antigens locus: RHcE Antigens: c, E
Haplotype r(y) is composed of what gene locus(i) and antigens locus: RHCE Antigens: C, E
Haplotype r is composed of what gene locus(i) and antigens locus: RHce Antigens: c, e
Haplotype R(o) is composed of what gene locus(i) and antigens locus: RHD, RHce Antigens: c, e
Most D to least D antigen haplotypes ↑ R2R2, R1R2, R1R1, R2r, Ror, R1r ↓
Frequency of D antigen in White and Black population White 85% , Black 92%
Frequency of C antigen in White and Black population White 70% , Black 27%
Frequency of E antigen in White and black population White 30% , Black 22%
Frequency of c antigen in White and Black population White 80% , Black 96%
Frequency of e antigen in White and Black population White 98% , Black 98%
Haplotype Inherited allele from 1 parent
Genotype Inherited haplotypes (from both parents)
Most probable genotype (MPG) Determined from typing results, haplotype frequencies and family studies
Phenotype Derived from cell typing results – Often symbolized as the most probable genotype
Created by: farrahrm