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Infection, Ch 9


filamentous bacteria bacteria that resemble fungi. (Mycobacterium tuberculosis)
spirochetes motile bacteria
true bacteria divide by binary fission, cocci, bacilli, vibrios, spirilla. Most diseases in this category.
mycoplasma smallest and most simple member
rickettsia intracellular parasite, bacteria
bacteria prokaryotic unicellular microorganism, no nuclie, mitochondria, or membrane-bound organelle
chlamydia intracellular bacteria, but more complex than rickettsia
Gram negative does not retain crystal violet dye, LPS coating that produces endotoxin
pili way bacteria adhese for colonization. thin-rod like projections from bateria surface
exotoxins proteins released during bacterial growth; immunogenic-produce antitoxins. vaccine available for DTP
Endotoxins LPS, lipopolysaccharides, gram neg bacteria-pyrogenic, released during lysis of bacteria, antibiotics can't prevent, cause of septic shock, DIC.
IgA protease breaks down Fc receptor. bacterial protective mechanism by menigitis causing microbes-S. pneumoniae, H. influenza, N. meningitidis, N. gonhorrhoeae
Teichoic acid found in gram positive cell wall that resists against complement-mediated lysis
Clostridia anaaerobic, produce most powerful toxins known-bolutism, blocks ACh-causing flaccid paralysis; tetanus, gas gangrene, Clostridum difficile-diarrhea.
bacterial superantigens toxins that increase adherence of MCH and t-cell receptors, overproduction of cytokines. TSS, scarlet fever, food poisoning
Beta lactamase enzyme that destroys penicillin
Fungi eukaryotic microorganism, thick rigid cell walls with capacity to form a variety of complex structures.
mycosis fungal infection
dermatophyte tinea, skin mycoses; ringerworm, etc.
Viral infection simple microorganism, do not possess any of the metabolic organelles found in bacteria. intracellular parasites. RNA invade host and replicate
reverse transciptase create double strand DNA, DNA provirus takes over cells DNA.
exogenous pyrogens interleukins 1 & 6 (IL1, IL6). interferon (IFN), tumor necrosis factor (TNF. raise thermoregulatory set point.. (exogeneous pyrogens indirectly affect hypothalamus through endogenous pyrogens)
batericidal antibiotics kill the organsim
bacteriostatic antibiotics inhibit growth until the organism is destroyed by own immune system
AZT azidothymidine, antiviral that suppresse reverse transcriptase. HIV can mutate & resistant
Dead bacterial vaccines pneumococcal pneumonia-not very immunogenic in children; children receive conjugated vaccine that is more effective
conjugated bacterial vaccine
Created by: Sniffen group