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blood gases;buffers
| Question | Answer |
|---|---|
| pH | index of acidity or alkalinity of the blood |
| blood gases | body's mechanism to maintain acid-base balance |
| acidosis | metabolic state that leads to acidema |
| alkalosis | metabolic state that leads to alkaemia |
| normal pH | 7.35-7.45 |
| acid | substance that can yield a hydrogen ion or hydronium ion when dissolved in water |
| base | substance that will yield a hydroxyl(OH-) ion when dissolved in water |
| K value | relative strenth of acids and bases and their ability to dissociate in water |
| buffer | combination of a weak acid or base and its salt so that it resists changes in pH. |
| pCO2 | measurement of tension or pressue of carbon dioxide dissolve in blood |
| pCO2 reference range | 35-45mmHg |
| pO2 | meansurement of tension or pressure of oxygen dissolved in blood |
| pO2 reference range | 80-110mmol/L |
| decreased pO2 is seen in... | decreased pulmanary ventilation |
| acid-base balance | maintenance of H+; increased H+, decreased pH; decreased H+, increased pH |
| bicarbonate-carbonic acid | buffer in highest concentration in plasma |
| Henderson-Hasselbalck equation | relates pH, HCO3, pCO2 |
| hemoglobin buffer | transports acid from tissues to lungs |
| phosphate buffer | intracellular buffer |
| albumin/other proteins | buffers system that binds H+ because of net negative charge |
| respiratory acid-base disorder | caused by ventilatory dysfunction |
| metabolic acid-base disorder | caused by renal dysfunction |
| compensation | body's attempt to restore acid-base balance |
| fully compensated | body pH has returned to normal range |
| partially compensated | body pH is approaching normal range |
| metabolic acidosis | decrease pH and decreased HCO3- |
| metabolic alkalosis | increase pH and increased HCO3- |
| respiratory acidosis | decrease pH and increased CO2 |
| respiratory alkalosis | increase pH and decreased CO2 |
| anion gap | eastimate of unmeasured anions and cations |