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Rickettsia...

QuestionAnswer
Are Rickettsiae, Chlamydiae, and Mycoplasmas related taxonomically? Nope!
What type of cell makes up Rickettsiae, Chlamydiae, and mycoplasmas? Prokaryotic
What is the primary mode of laboratory diagnosis for rickettsia, chlamydiae, and mycoplasmas? Serological tests
Is Bacteria DNA and RNA positive or 0? +
Is chlamydiae RNA and DNA positive or 0? +
Is Mycoplasmas RNA and DNA positive or 0? +
Is rickettsiae RNA or DNA positive or 0? +
Is virus RNA or DNA positive or 0? 0
+ or 0 for bacteria as obligate intracellular parasites? 0
+ or 0 for chlamydiae as obligate intracellular parasites? +
+ or 0 for rickettsiae as obligate intracellular parasites? +
+ or 0 for mycoplasmas as obligate intracellular parasites? 0
+ or 0 for viruses as obligate intracellular parasites? +
Does bacteria have growth on cell free media? +
Does chlamydiae have growth on cell free media? 0
Does rickettsiae have growth on cell free media? 0
Does mycoplasmas have growth on cell free media? +
Does viruses have growth on cell free media? 0
Are bacteria susceptible to antibacterial drugs? +
Are chlamydiae susceptible to antibacterial drugs? +
Are rickettsiae susceptible to antibacterial drugs? +
Are mycoplasmas susceptible to antibacterial drugs? +
Are viruses susceptible to antibacterial drugs? 0
Do bacteria reproduce via binary fusion? +
Does chlamydiae reproduce via binary fusion? +
Does rickettsiae reproduce via binary fusion? +
Does mycoplasmas reproduce via binary fusion? +
Does viruses reproduce via binary fusion? 0
Does rickettsiae stain using gram stain? yes, but not well
What is the morphology of rickettsiae? small, coccobacillary and pleomorphic
What kind of reproduction style does rickettsiae have? Intracytoplasmic
How is rickettsiae released from an infected cell? Bursting the cell
Can rickettsiae grow on agar media? No it requires viable cells to grow
What kind of pathenogenesis does rickettsiae have? predilection for endothelial cells of blood vessels peripheral vasculitis with leakage and thrombus formation
What kind of stain can be used on rickettsiae? Giemsa Stain
How is rickettsiae typically spread to humans? Arthropods... except for Q fever
How is Rickettsiae presented normally in humans? variable presentation, can be benign to fulminating
What are the prominent clinical feature of rickettsiae? abrupt onset, fever, headache and myalgia and petechial rash,
What organs can be affected by rickettsiae? heart, liver, spleen, kidneys
What is death due to in rickettsiae? vascular callapse and or renal failure
What diseases can be born from rickettsiaceae? epidemic typhus, murine typhus, and Rocky mountain spotted fever, Q-fever, human monocytic ehrlichiosis, human granulocytic ehrlichiosis
What is another name for Epidemic Typhus? louse borne typhus
What is the etiological agent for Epidemic typhus? Rickettsia prowazeki
What is the vector for epidemic typhus? human body louse
What is the recrudescence of latent infection with no rash involve in epidemic typhus? Brill-Zinsser disease
What is another name for Murine typhus? endemic typhus
What is the etiological agent for murine typhus? Rickettsia typhi
What is the vector involved with murine typhus? Rat flea and cat flea
What is another name for Rocky Mountain spotted fever? American spotted fever
What is the etiological agent for rocky mountain spotted fever? Rickettsia rickettsii
What is the vector for rocky mountain spotted fever? Ixodes species ticks
How many cases of rocky mountain spotted fever are reported each year in the US? 2000
How many cases of rocky mountain spotted fever are reported each year in KY? 5
When did Howard T. Ricketts discover rickettsiae and how it was transmitted? 1909
When did Stanislaus von Prowazek first describe rickettsiae in lice? 1913
What is the etiological agen for Q fever? Coxiella burnetti
What vectors are associated with q-fever? ticks, but usually dust and aerosols in humans
What is the etiological agent for human monocytic ehrilichiosis? Ehrlichia chaffeensis
What is the vector associated with monocytic ehrlichiosis? Amblyomma americanum
What is another name for amblyomma americanum? Lone star tick
What is the reservoir for the lone star tick? white tailed deer
What is the etiological agent for human granulocytic ehrlichiosis? Anaplasma phagocytophilia
What is the vector for human granulocytic ehrlichiosis? Ixodes scapularis
What is the reservoir for ixodes scapularis? White-footed mouse
Where is human granulocytic ehrlichiosis normally found? Eastern US
Does rickettsiae grow on artificial media? Nope!
How can you cultivate Rickettsiae? in a cell culture and embyonated eggs
What serological tests are normally used in the diagnosis of a rickettsial infection? Weil-Felix agglutination Enzyme immunoassay Indirect immunofluorescence
What are the two forms of Chlamydiae? Elementary body and Reticulate body
What is meant by elementary body in reference to chlamydiae? adapted for extracellular survival
What is meant by reticulate body in reference to chlamydiae? adapted for intracellular growth
Will chlamydiae grow on agar media? Nope
What is another way to explain how chlamydiae will not grow on agar media? Obligate intracellular microbes
What is the unique reproductive cycle of chlamydiae? EB (infectious form) to host cell to RB to cell busts to EBs
What type of cells does chlamydiae have an affinity for? non-ciliated epithelial cells of mucous membranes
What are some examples of non-ciliated epithelial cells of mucous membranes? conjunctiva, genitourinary tract and viz
What diseases are related to chlamydiae? trahoma, lymphogranuloma venerem, STI, Ornithosis, Pharyngitis, pneumonia
What is the etiological agent for trachoma, lymphogranuloma venereum, and the STI? Chlamydia trachomatis
What is the etiological agent for Ornithosis (zoonosis)? Chlamydophila psittaci
What is the etiological agent is associated with pharyngitis and pneumonia, in the chlamydiae genus? Chlamydophila pnemoniae
What is chlamydiae suspected to be an etiological agen for? atherosclerosis, arthritis, asthma, and alzheimer's
What is the morphology of mycoplasmas? lack cell wal, pleomorphic
What what is the size of the mycoplasmas? .3-.8 micrometers
Will mycoplasmas gram stain? Nope
What kind of media will mycoplasmas grow on? agar media
What is the colony morphology for mycoplasmas? small minute colonies, 10-300 micro meters
What mycoplasmas is responsible for pneumonia? mycoplasma pneumoniae
What mycoplasma is responsible for urethritis? Ureaplasma urealyticum
What is the mycoplasma is a normal flora in the gu tract in healthy adults mycoplasma hominis
What did the Irvinton House in richmond, KY treat? Trachoma
How many hospitals in the US between 1920 to 1950 treated trachoma? 4
Created by: jnwells03