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Virology lectures


Baltimore type I dsDNA
Baltimore type II ssDNA
Baltimore type III dsRNA
Baltimore type IV +ssRNA --> -ssRNA
Baltimore type V -ssRNA
Baltimore type VI +ssRNA --> -ssDNA
Rotavirus severe gastroenteritis in infants (6mo-2yr) viral NSP4 protein acts as an enterotoxin high genetic variability: segmented dsRNA genome and RNA-dependent RNA polymerase vaccines available
Norovirus gastroenteritis: adults and school-age children, food-borne, cruise-ships environmentally stable virus high genomic variability no lasting immunity no vaccine available
Astrovirus gastroenteritis in infants (less severe than rota), elderly and immunocompromised
Adenovirus multiple strains, enteric, respiratory, ocular infections, systemic infections severe dz in immunocompromised
Rhinovirus picornavirus family 50% of common colds
Coronavirus 2nd most prevalent cause of common colds SARS
Paramyxovirus family Parainfluenza virus Respiratory syncytial virus Metapneumovirus Measles, Mumps, Rubella Viruses Hendra and Nipah
Parainfluenza virus croup
Respiratory syncytial virus severe lower respiratory dz in infants very contagious no vaccine, antiviral therapies avail.
Metapneumovirus similar to RSV, less severe
Measles and mumps viruses systemic infection effective vaccine available
Hendra and Nipah Viruses newly emerging, animal reservoirs
Created by: rthorsted