Virology
Help!
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| Baltimore type I | dsDNA
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| Baltimore type II | ssDNA
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| Baltimore type III | dsRNA
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| Baltimore type IV | +ssRNA --> -ssRNA
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| Baltimore type V | -ssRNA
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| Baltimore type VI | +ssRNA --> -ssDNA
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| Rotavirus | severe gastroenteritis in infants (6mo-2yr)
viral NSP4 protein acts as an enterotoxin
high genetic variability: segmented dsRNA genome and RNA-dependent RNA polymerase
vaccines available
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| Norovirus | gastroenteritis: adults and school-age children, food-borne, cruise-ships
environmentally stable virus
high genomic variability
no lasting immunity
no vaccine available
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| Astrovirus | gastroenteritis in infants (less severe than rota), elderly and immunocompromised
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| Adenovirus | multiple strains, enteric, respiratory, ocular infections, systemic infections
severe dz in immunocompromised
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| Rhinovirus | picornavirus family
50% of common colds
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| Coronavirus | 2nd most prevalent cause of common colds
SARS
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| Paramyxovirus family | Parainfluenza virus
Respiratory syncytial virus
Metapneumovirus
Measles, Mumps, Rubella Viruses
Hendra and Nipah
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| Parainfluenza virus | croup
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| Respiratory syncytial virus | severe lower respiratory dz in infants
very contagious
no vaccine, antiviral therapies avail.
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| Metapneumovirus | similar to RSV, less severe
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| Measles and mumps viruses | systemic infection
effective vaccine available
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| Hendra and Nipah Viruses | newly emerging, animal reservoirs
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Created by:
rthorsted
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