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Med Micro parasites
exam3
Question | Answer |
---|---|
Entamoeba hartmanni | "small histolytica stool specimen troph- 1 nucleus, central karyosome cytoplasm- fine granular cyst- 4 nuclei, elongated chromatoid bodies, rounded ends |
Endolimax nana | stool specimen troph-1 nucleus, blot like karyosome cyst- 4 nuclei, blot like karyosome no chromatoid bodies |
Lodameoba buetschlii | stool specimen troph-1 nucleu;, large, central karyosome, retractile granules cytoplasm- coarsely ground, vaculated cyst- 1 large nucleus, eccentric karyosome, compact, well defined glycogen mass |
Entamoeba polecki | stool spec troph- 1 nucleus, small discrete karyosomal chromatin cytoplasm- coarsely granular, vaculated cyst- 1 nucleus, sm eccentric karyosome(pleomorphic) cytoplasm - small inclusions/mass |
Retortamonas intestinales | rare cyst - 1 nuclei, fibrils shaped like "birds beak" troph- slightly pear shaped or oval, 1 nucleus; cytostome extends half way; 2 flagella, posterior/anterior |
Dientamoeba fragilis | found in mucosal lining of lg intestines; unclear life cycle usually asymptomatic/diarrhea, abdominal pain no cyst troph- binuclear/1 |
4 morphologic forms of HEMOFLAGELLATES | amastigote promastigote epimastigote trypomastigote |
amastigote | round, 1 nucleus, kinetoplast dot-like blepharoplast, gives rise to axomneme single parabassal body, adjacent to blepharoplast no flagella |
promastigote | long, slender body with free flagella 1 lg nucleus near center kinetoplast is anterior to nucleus rise to axoneme and flagella |
epimastigote | body is long, wider 1 lg nucleus, posterior kinetoplast anterior to nucleus undulating membrane half way into free flagella |
trypomastigote | C/U shape on stained blood slides; curve around RBCs long, slender body posterior kinetoplast w/ undulating membrane whole length of body flagella whole length |
specimens of choice for hemoflagellates | blood lymph node/ulcer aspirations bone marrow tissue biopsies CSF |
Leshmania braziliensis | specimen- biopsy of infected ulcer diagnostic stage- amastigote found Brazil, Columbia, Ecuador, Venezuela, Peru vector - Lutzomyia/psychodopygus sandfly res |
Mucocutaneous Leishmaniasis | infection of Leshmania braziliensis large ulcers in oral/nasal mucosa; destruction of nasal septum |
Leishmania donovani chagasi Leishmania donovani donovani Leishmania donovani infantum | Middle East vector - sandfly reservoirs- chagasi-dog, cat, fox donovani- none/fox infantum- dog, fox, jackal, porcupine |
Kalaazar or dum dum fever | Visceral leishmaniasis enlarged liver/spleen; darkening of skin "black fever" |
Leishmania tropica group | L. aethiopica L. major L. tropica |
Leishmania tropica vector; attacks what human organ; reservior; infectious phase | Phlebotomus sandfly; lymphoid tissue of skin; possibly dogs; amastigote |
Leishmania aethiopica reservior | rock hyrax |
Leishmania major reservior | gerbils; rodents |
"Old World Leishmaniasis"; "Oriental Sore"; "Baghdad/Delhi boil" | L. Tropica; Cutaneous Leishmaniasis; develops a small red papule with intense itching |
Diffuse cutaneous leishmaniasis (DCL) | immune system fails and self-healing doesn't occur |
Trypanosoma brucei gambiense | vector: Glossina palpalis/tachinoides tsetse flies humans infected by trypomastigote (diagnositic); travels to lymph system then CNS multiply by binary fission found in West/Central Africa |