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CH5 Slides 8-13+27

What are the factors that can cause a higher Recurrence risk? More than one family member has disease Member of family has severe expression of disease If the proband is in the lesser affected gender If disease is in more closely-related family member
What is difference in Nature vs Nurture? Nature is genetic, nurture is environment or lifestyle related.
What term is used for identical twins? How about fraternal twins? Identical - monozygotic Fraternal - dizygotic
What is a concordant trait? Discordant trait? Concordant trait is when twins share a common genetic trait. Dicordant trait is when they don't (only one twin has trait)
What are adoption studies and what are they intended to study? When children who are born to parents who have a disease and are adopted by a different family, they are studied to see if the disease occurs. This is one way to study if a disease is nature or nurture.
What is a congenital disease? Disease that occurs at birth, most congenital diseases are multi-factorial.
Examples of multi-factorial diseases hyper-cholestoralemia, coronary heart disease.
Created by: preston713