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DEENT 1-2
BDK
| Pharmacologic Category | Generic Name | Brand Name | Classification | Common Indications | Essential Knowledge |
|---|---|---|---|---|---|
| Opioid analgesic and expectorant | codeine and guaifenesin (PO) | Robitussin AC, Cheratussin AC | CS-V | Cough | Key Side Effects: dizziness, somnolence, constipation, respiratory depression (dose-related) Other Notes: opioid-containing cough and cold products no longer indicated for use in patients <18 years of age |
| Histamine (H1) blocker and opioid analgesic | promethazine and codeine (PO) | Phenergan with Codeine | CS-V | Cough | dizziness, somnolence, xerostomia, blurred vision, constipation, respiratory depression (dose-related) BW:concomitant use of opioids with benzodiazepines or other CNS depressants No codeine cough for <18 years of age |
| Histamine (H1) blocker | olopatadine (ophthalmic) | Pataday, Patanol | OTC | Allergic conjunctivitis | Key Side Effects: ocular burning, discomfort, dryness |
| Histamine (H1) blocker | levocetirizine (PO) | Xyzal | OTC | Allergic rhinitis | Key Side Effects: diarrhea, drowsiness, headache |
| Histamine (H1) blocker | cetirizine (PO) loratadine (PO) fexofenadine (PO) | Zyrtec Claritin Allegra | OTC | Allergic rhinitis | Key Side Effects: drowsiness, dizziness, headache |
| Histamine (H1) blocker | hydroxyzine (PO, IV) | Atarax, Vistaril | Atarax, Vistaril | Key Side Effects: dizziness, somnolence, xerostomia, blurred vision, QTc prolongation | |
| Histamine (H1) blocker | diphenhydramine (PO, IV) | Benadryl | PO: OTC | Allergic rhinitis, allergic reaction, insomnia | Key Side Effects: drowsiness, constipation, xerostomia, urinary retention, cognitive impairment Other Notes: for OTC use, do NOT use in children < 6 years of age |
| Histamine (H1) blocker | azelastine (intranasal) | Astepro | OTC | Allergic rhinitis | Key Side Effects: headache, nasal dryness, epistaxis, bitter taste, drowsiness |
| Corticosteroid | triamcinolone (intranasal) fluticasone (intranasal) | Nasacort FLonase | OTC OTC | Allergic rhinitis | Key Side Effects: nasal dryness, epistaxis, nasal burning, headache |
| Alpha (α1) agonist | pseudoephedrine (PO) | Sudafed | OTC | Nasal congestion | Key Side Effects: Increased blood pressure, tachycardia, palpitations, insomnia, restlessness Other notes: sold behind the counter, avoid during first trimester of pregnancy |
| Antitussive | benzonatate (PO) | Tessalon Perles | Cough | Key Side Effects: sedation, nasal congestion, chills, chest numbness, bronchospasm Other Notes: do not break capsule because it may cause choking | |
| Antitussive | dextromethorphan (PO) | Delsym | OTC | Cough | Key Side Effects: nausea, drowsiness, dizziness, constipation Other Notes: CI within 14 days of MAOI |
| Expectorant | guaifenesin (PO) | Mucinex, Robitussin, Robafen | OTC | Cough | Key Side Effects: nausea, vomiting, dizziness, headache, diarrhea, stomach pain |
| Corticosteroid | clobetasol (topical) | Temovate, Clobex | Psoriasis, atopic dermatitis | Key Side Effects: burning of skin, dryness of skin, hypopigmentation, secondary infection Other Notes: do not use for > 2 weeks because it may cause adrenal suppression | |
| Antiseptic | chlorhexidine (topical, PO) | Hibiclens, Peridex | Hibiclens: OTC | Skin cleanser, periodontitis, gingivitis | Key Side Effects: dysgeusia, increased tartar formation, mouth discoloration, mouth irritation |
| Retinoic acid derivative | adapalene (topical) | Differin | OTC | Acne | Key Side Effects: xeroderma, skin exfoliation, erythema, stinging, burning, pruritus |
| Pediculocide | permethrin (topical) | Nix, Elimite | Nix: OTC | Lice, scabies | Key Side Effects: itching, burning, redness, swelling of scalp |
| Calcineurin inhibitor | cyclosporin (ophthalmic) | Restasis | Keratoconjunctivitis sicca | Key Side Effects: ocular burning, stinging, pruritus, foreign body sensation, hypersensitivity reaction | |
| Prostaglandin analog | latanoprost (ophthalmic) | Xalatan, Xelpros, Iyuzeh | Elevated IOP | Key Side Effects: eyelash growth, conjunctival hyperemia, ocular pruritus, iris color change, periocular hyperpigmentation, blurred vision | |
| Prostaglandin analog | bimatoprost (ophthalmic) | Lumigan, Latisse | Elevated IOP, eyelash hypotrichosis | Key Side Effects: eyelash growth, conjunctival hyperemia, ocular pruritus, iris color change, periocular hyperpigmentation, blurred vision | |
| Non-selective beta-blocker | timolol (ophthalmic) | Timoptic, Timoptic XE, Istalol | Elevated IOP | Key Side Effects: blurred vision, ocular stinging and burning | |
| Alpha2 agonist | brimonidine (ophthalmic) | Alphagan P, Lumify | Lumify: OTC | Elevated IOP Ocular redness | Key Side Effects: ocular hypersensitivity, drowsiness, allergic conjunctivitis, conjunctival hyperemia, ocular pruritus Other Notes: CI with MAOI therapy |