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CV 1-2

BDK

Pharmacologic CategoryGeneric NameBrand NameCommon IndicationsEssential Knowledge
Alpha1 agoits (predominantly), beta 1, beta2 agonist norepinephrine (OV) Levophed Shock Key Side Effects: tachyarrhythmias, peripheral ischemia US Boxed Warning: extravasation (central line administration preferred)
Beta1, beta 2 and alpha 1 agonist epinephrine (IV, IM, SQ) Adrenalin, epipen advanced cardiac life support, shock, anaphylaxis, bradycardia Key Side Effects: tachyarrhythmias, peripheral ischemia, hyperglycemia
Direct arterial vasodilator hydralazine (PO, IV) - HTN Key Side Effects: hypotension, drug-induced lupus-like syndrome Other Notes: CI in CAD
Alpha2 agonist clonidine (PO, transdermal) PO: Catapres, Transdermal: Catapres-TTS HTN, ADHD Key Side Effects: xerostomia, drowsiness, contact dermatitis (transdermal), hypotension US Boxed Warnings: avoid epidural use Other Notes: do not discontinue abruptly; taper to reduce rebound HTN
Non-selective beta- blocker propranolol (PO) Inderal LA, Inderal XL HTN, CAD, migraine prophylaxis Key Side Effects: bradycardia, hypotension Other Notes: masks symptoms of hypoglycemia
Non-selective beta- blocker and alpha1 blocker labetalol (PO, IV) Trandate PO: HTN, IV: hypertensive crisis Key Side Effects: bradycardia, hypotension Other Notes: masks symptoms of hypoglycemia
Non-selective beta- blocker and alpha1 blocker carvedilol (PO) Coreg, Coreg CR HF, AF (rate control), CAD, HTN Key Side Effects: bradycardia, hypotension Other Notes: masks symptoms of hypoglycemia
Beta1-selective beta- blocker esmolol (IV) Brevibloc HTN, AF (rate control), hypertensive emergency Key Side Effects: bradycardia, hypotension Other Notes: masks symptoms of hypoglycemia; CI with pulmonary hypertension
Beta1-selective beta- blocker nebivolol (PO) Bystolic HTN Key Side Effects: bradycardia, hypotension Other Notes: masks symptoms of hypoglycemia
Beta1-selective beta- blocker metoprolol succinate (PO) Toprol-XL HF, AF (rate control), CAD, HTN Key Side Effects: bradycardia, hypotension Other Notes: masks symptoms of hypoglycemia
Beta1-selective beta- blocker metoprolol tartrate (PO, IV) Lopressor AF (rate control), CAD, HTN Key Side Effects: bradycardia, hypotension US Boxed Warnings: avoid abrupt discontinuation Other Notes: masks symptoms of hypoglycemia
Beta1-selective beta- blocker atenolol (PO) Tenormin AF (rate control), CAD, HTN Key Side Effects: bradycardia, hypotension US Boxed Warnings: avoid abrupt discontinuation Other Notes: masks symptoms of hypoglycemia
Loop diuretic torsemide (PO) Soaanz Volume overload Key Side Effects: hypokalemia, hypomagnesemia, hyponatremia, hypotension
Loop diuretic furosemide (PO, IV) Lasix Volume overload Key Side Effects: hypokalemia, hypomagnesemia, hyponatremia, hypotension US Boxed Warnings: fluid and electrolyte loss
Mineralocorticoid receptor antagonist (MRA) spironolactone (PO) Aldactone HTN, HF, ascites Key Side Effects: gynecomastia, hyperkalemia, hypotension
Thiazide-related diuretic chlorthalidone (PO) Thalitone HTN Key Side Effects: hypokalemia, hyponatremia, photosensitivity, hypotension
Thiazide diuretic hydrochlorothiazide (PO) - HTN Key Side Effects: hypokalemia, hyponatremia, photosensitivity, hypotension
Non-dihydropyridine CCB verapamil (PO) Calan SR, Verelan AF (rate control), HTN, CAD Key Side Effects: bradycardia, constipation, peripheral edema, hypotension
Non-dihydropyridine CCB diltiazem (PO, IV) Cartia XT, Cardizem CD, Cardizem LA, Cardizem, Tiazac AF (rate control), HTN, CAD Key Side Effects: bradycardia, constipation, peripheral edema, hypotension
Dihydropyridine calcium channel blocker (CCB) nicardipine (PO, IV) Cardene Hypertensive crisis Key Side Effects: flushing, headache, peripheral edema, hypotension
Dihydropyridine calcium channel blocker (CCB) nifedipine ER (PO) Procardia XL, Adalat CC HTN, CAD Key Side Effects: peripheral edema, hypotension
Dihydropyridine calcium channel blocker (CCB) amlodipine (PO) Norvasc HTN, CAD Key Side Effects: peripheral edema, hypotension
ARB and neprilysin inhibitor (ARNI) valsartan and sacubitril (PO) Entresto HF Key Side Effects: hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) Other Notes: Do not use within 36 hours of an ACE inhibitor
Angiotensin II receptor blocker (ARB irbesartan (PO) losartan (PO) olmesartan (PO) valsartan (PO) Avapro Cozaar Benicar Diovan HTN, HF, CAD Key Side Effects: hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy)
Angiotensin-converting enzyme (ACE) inhibitor benazepril (PO) enalapril (PO) lisinopril (PO) ramipril (PO) Lotensin Vasotec Prinivil, Zestril Altace HTN, HF, CAD Key Side Effects: cough, hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy)
Created by: beezy41
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