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CNS 1

BDK

Pharmacologic CategoryGeneric NameBrand NameCommon IndicationsEssential Knowledge
Tricyclic antidepressant (TCA doxepin (PO) Silenor Insomnia Key Side Effects: somnolence, sedation, nausea US Boxed Warnings: increased risk of suicidal thinking and behavior in children, adolescents, and young adults Other Notes: CI within 14 days of MAOI; do not discontinue abruptly
Tricyclic antidepressant (TCA nortriptyline (PO) Pamelor MDD, diabetic neuropathy, migraine prophylaxis dizziness, drowsiness, orthostatic hypotension, sexual dysfunction, xerostomia, blurred vision, constipation BW: increased risk of suicidal thinking and behavior in youth CI within 14 days of MAOI; do not discontinue abruptly
Tricyclic antidepressant (TCA amitriptyline (PO) Elavil MDD, diabetic neuropathy, migraine prophylaxis dizziness, drowsiness, orthostatic hypotension, sexual dysfunction, xerostomia, blurred vision, constipation BW: increased risk of suicidal thinking and behavior in youth CI within 14 days of MAOI; do not discontinue abruptly
Serotonin reuptake inhibitor trazodone (PO) Desyrel Insomnia, MDD Key Side Effects: sedation, headache, dizziness, xerostomia, nausea, priapism US Boxed Warnings: increased risk of suicidal thinking and behavior in children, adolescents and young adults
Selective serotonin reuptake inhibitor (SSRI) citalopram (PO) fluoxetine(PO) escitalopram (PO) paroxetine (PO) sertraline (PO) Celexa Prozac Lexapro Paxil Zoloft MDD drowsiness, insomnia, nausea, vomiting, xerostomia, sexual dysfunction, headache, diaphoresis BW: increased risk of suicidal thinking and behavior in youth : CI within 14 days of MAOI do not discontinue abruptly (all except fluoxetine)
Serotonin- norepinephrine reuptake inhibitor (SNRI) desvenlafaxine (PO) venlafaxine (PO) Pristiq Effexor XR MDD headache, xerostomia, nausea, vomiting, constipation, decreased appetite, insomnia. diaphoresis, hypertension, sexual dysfunction BW: increased risk of suicidal thinking and behavior in youthj CI within 14 days of MAOI; do not discontinue abruptly
Serotonin- norepinephrine reuptake inhibitor (SNRI) duloxetine (PO) Cymbalta MDD, neuropathic pain headache, xerostomia, nausea, vomiting, constipation, decreased appetite, insomnia. diaphoresis, hypertension, sexual dysfunction BW: increased risk of suicidal thinking and behavior in youthj CI within 14 days of MAOI; do not discontinue abruptly
Selective norepinephrine reuptake inhibitor atomoxetine (PO) Strattera ADHD Key Side Effects: hypertension, tachycardia, headache, xerostomia, nausea, vomiting, constipation, decreased appetite, insomnia US Boxed Warnings: increased risk of suicidal ideation in children or adolescents Other Notes: CI within 14 days of MAOI
Norepinephrine- dopamine reuptake inhibitor bupropion (PO) Wellbutrin SR, Wellbutrin XL MDD tachycardia, headache, agitation, dizziness, insomnia, weight loss, xerostomia, increased risk of seizures BW: increase suicidal thinking in the youth,
Alpha2 antagonist mirtazapine (PO) Remeron MDD Key Side Effects: drowsiness, weight gain, xerostomia, increased appetite, constipation US Boxed Warnings: increased risk of suicidal thinking and behavior in children, adolescents, and young adults
Created by: beezy41
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