Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
GI 1-2
BDK
| Pharmacologic Category | Generic Name | Brand Name | Classification | Common Indications | Essential Knowledge |
|---|---|---|---|---|---|
| Gastrointestinal protectant | sulcrafate (PO) | Carafate | duodenal ulcers | Key Side Effects: constipation, bezoar formation Other Notes: take on an empty stomach; many drug interactions due to reducing absorption of other drugs | |
| Proton pump inhibitor (PPI) | dexlansoprazole (PO) esomeprazole (PO, IV) lansoprazole (PO) omeprazole (PO) pantoprazole (PO, IV) | Dexilant Nexium Prevacid Prilosec Protonix | PO nexium, prevacid and prilosec are OTC | GERD, PUD, erosive esophagitis, SUP | Key Side Effects: headaches, abdominal pain, nausea, diarrhea, bone fracture, vitamin B12 deficiency, hypomagnesemia, increased risk of Clostridioides difficile associated diarrhea (CDAD) |
| Antidiarrheal | diphenoxylate and atropine (PO) | Lomotil | CS-V | Diarrhea | Key Side Effects: nausea, confusion, drowsiness, dizziness, xerostomia, tachycardia, urinary retention Other notes: do not use in diarrhea associated with enterotoxin- |
| Histamine (H1) antagonist | meclizine (PO) | Bonine | OTC | Motion sickness, vertigo | Key Side Effects: drowsiness, dry mouth, blurry vision |
| Histamine (H1) antagonist | promethazine (PO, IM, IV, PR) | Phenergan | Motion sickness, nausea, vomiting | Key Side Effects: drowsiness, dry mouth, blurred vision, QTc prolongation, EPS US Boxed Warnings: potential for fatal respiratory depression in patients < 2 years old; injection can cause peripheral extravasation (preferred parenteral route is IM) | |
| Selective serotonin in (5-HT3) antagonist | ondansetron (PO, IV) | Zofran | Nausea, vomiting | Key Side Effects: headache, fatigue, constipation, QTc prolongation | |
| Dopamine (D2) antagonist | metoclopramide (PO, IV) | Reglan | Gastroparesis, GERD, nausea, vomiting | Key Side Effects: drowsiness, dystonia, akathisia, EPS, QTc prolongation, diarrrhea, hyperprolactinemia, US Boxed Warnings: may cause tardive dyskinesia, do not use >12 weeks, Other notes: CI with GI obstruction, perforation, or hemorrhage | |
| Histamine (H2) antagonist | famotidine (PO, IV) | Pepcid, Zantac 360 | PO OTC | GERD, erosive esophagitis, SUP | Key Side Effects: headache, constipation, diarrhea, mental status changes |
| Corticosteroid | hydrocortisone (PO, IV, topical) | Topical: Cortaid IV: Solu-Cortef | Topical: OTC | Topical: Inflammation, rash PO/IV: Acute illness, adrenal insufficiency | Key Side Effects: hyperglycemia, increased appetite with weight gain, depression, irritability, anxiety, restlessness, insomnia, osteoporosis (chronic use), Cushing's syndrome (chronic use) Other Notes: risk of adrenal suppression with prolonged use |
| Corticosteroid | prednisone (PO) | Deltasone, Rayos | Inflammatory diseases, COPD exacerbation, asthma exacerbation, acute gout | Key Side Effects: hyperglycemia, increased appetite with weight gain, depression, irritability, anxiety, restlessness, insomnia, osteoporosis (chronic use), Cushing's syndrome (chronic use) Other Notes: risk of adrenal suppression with prolonged use | |
| Corticosteroid | prednisolone (PO | Orapred | Inflammatory diseases, COPD exacerbation, asthma exacerbation, acute gout | Key Side Effects: hyperglycemia, increased appetite with weight gain, depression, irritability, anxiety, restlessness, insomnia, osteoporosis (chronic use), Cushing's syndrome (chronic use) Other Notes: risk of adrenal suppression with prolonged use | |
| Corticosteroid | methylprednisolone (PO, IM, IV) | Medrol, Solu-Medrol | Inflammatory diseases, COPD exacerbation, asthma exacerbation, acute gout | Key Side Effects: hyperglycemia, increased appetite with weight gain, depression, irritability, anxiety, restlessness, insomnia, osteoporosis (chronic use), Cushing's syndrome (chronic use) Other Notes: risk of adrenal suppression with prolonged use | |
| Corticosteroid | dexamethasone (PO, IV) | DexPak, DoubleDex | Inflammatory diseases, cerebral edema, CINV | Key Side Effects: hyperglycemia, increased appetite with weight gain, depression, irritability, anxiety, restlessness, insomnia, osteoporosis (chronic use), Cushing's syndrome (chronic use) Other Notes: risk of adrenal suppression with prolonged use | |
| Stool softener | docusate (PO) | Colace | OTC | Prevent straining during defecation | Other Notes: do not use with mineral oil |
| Stimulant laxative | senna (PO) | Ex-Lax, Senokot | OTC | Constipation | Key Side Effects: abdominal cramping, electrolyte imbalance |
| Osmotic laxative | Lactulose (PO) | Enulose, Constulose | Constipation, hepatic encephalopathy | Key Side Effects: abdominal cramps, abdominal distention, diarrhea, flatulence | |
| Osmotic laxative | polyethylene glycol 3350 (PO) | Miralax | OTC | Constipation | Key Side Effects: abdominal cramping, electrolyte imbalance Other Notes: CI with bowel obstruction |
| Guanylate cyclase C agonist | linaclotide (PO) | Linzess | IBS-C, opioid-induced constipation | Key Side Effects: diarrhea, abdominal pain, US Boxed Warnings: do not use in patients <2 years of age (risk of death due to dehydration), Other Notes: mechanical gastrointestinal obstruction | |
| Anticholinergic; Antispasmodic | dicyclomine (PO) | Bentyl | IBS | Key Side Effects: drowsiness, blurred vision, dizziness, xerostomia, constipation Other Notes: CI in gastrointestinal obstruction, reflux esophagitis, acute hemorrhage with cardiac instability, obstructive uropathy, glaucoma |
Created by:
beezy41
Popular RICA sets