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11/5

Hearing Sciences

QuestionAnswer
What did Theodor Schwann discover? Schwann cells on nerve cells, pepsin, striated muscles in the upper esophagus, embryological process, and coined the term metabolism
What is an acoustic neuroma also called? A vestibular schwanoma
What is an acoustic neuroma? a small tumor on the Schwann sheathing
What does the terminal arbor synapse with? the cochlear nucleus
What does it mean that the terminal arbor is presynaptic? it precedes the synapse between it and the next cells.
What does the terminal arbor do? it receives the impulse that is racing down the axon
What is the direction of nerve conduction? dendrites, axon, cell body, axon, terminal arbor
Where does nerve conduction start? in the dendrites
What happens if the nerve impulse is strong enough? it will continue from the dendrites down through the first axon, cell body, the second axon, and onto the terminal arbor
What is a synapse? the gap between the hair cell and the dendrites of the 8th nerve cells
Where are the initial axon's dendrites located? in the post-synaptic region
What is sensitive to neurotransmitter? the initial axon's dendrites
Where are the terminal arbor's dendrites located? in the presynaptic region
What produces neurotrasmitter? the terminal arbor's dendrites
What is the neurotransmitter of the 8th nerve bipolar neurons? Acetylcholine (ACH)
WHat do you use the presence of a synapse for? to count the sequence of neurons
What is the first synapse? hair cell to afferent neurons
What are 8th nerve neurons? first order neurons
Where is the second synapse? at cochlear nuclei in the brain stem
What are all neurons leaving the cochlear nuclei considered? second order neurons
What is the overall charge of the 8th nerve bipolar neuron cell interior? negative
What is the overall charge of the 8th nerve bipolar neuron cell exterior? positive
What are the features of an 8th nerve bipolar neuron cell interior? potassium constantly leaking from the interior, organic negative ions
What are the features of an 8th nerve bipolar neuron cell exterior? Contains sodium and chloride, more sodium though
What are inner spirals and tunnel radials? efferent nerves fibers (type 2)
What are radial and outer spiral fibers? afferent nerves fibers (type 1)
What do Afferent fibers synapse with? the cell body
What do Efferent fibers synapse with? the axon of the afferent fibers
What does each cochlear nucleus receive? ipsilateral radial and outer spiral fibers of the 8th nerve
What is important about the input the cochlear nucleus receives? it is the highest point in the auditory pathway that receives only ipsilateral input
What is ipsilateral input? same side input
What is contralateral input? different side input
What does the nerve cells membrane separates? intracellular and extracellular fluids
What do neurons at rest present? an uneven distribution of ions across the plasma membrane because the charges of the ions in the two fluids differ
What does the electrical difference between intracellular and extracellular fluids produce? an electrical potential
When does electrical potential exists? it is always there in a living subject whether the nerve is excited or not
What is the permanent potential of a nerve called? resting potential
What does intracellular fluid consist of? primarily potassium with a negatively charged ionic field
What does extracellular fluid consist of? primarily sodium and has a positively charged ionic field
How do the overall number of ions of a cell at rest compare? the positive ions are higher outside the cell than inside
What does protein in the plasma membrane allow for? ion channels that allow the passage of ions into and out of the plasma membrane
When will ligand-gated channels open? when chemically stimulated with a neurotransmitter
What stimulates the ligand-gated channels of afferent fibers? glutamate from inner hair cells
What stimulates the ligand-gated channels of outer hair cells? acetylcholine from efferent fibers
What are ligand-gated channels? little openings
What happens when glutamate is released? it moves across the synapse towards the dendrites of the afferent neuron
Where does glutamate come from? the base of the inner hair cells
What happens when glutamate stimulates ligand-gated ion channels? it opens, allowing Na+ to flow into the dendrites and K+ to flow out
What flow is greater when glutamate stimulates the ligand-gated channels? the inflow of Na+ is greater than the outflow of K+
What activates a voltage-gated channel? changes in the electrical potential difference near the channel
What do voltage-gated channels allow for? rapid and coordinated depolarization in the nerve cell
What is an action potential? a short lasting electrical event on the plasma membrane of a nerve cell
What is another name for an action potential? a nerve impulse
What is the resting potential? the difference between the intra and extra cellular fluids across the cell membrane
What is permeability? the ability of the cell membrane to allow ions to pass through
What is the most widely accepted theory on the flow of an electron current through the neuron starts with what? a change in the permeability of the cell membrane to potassium and sodium as a function of excitation of the nerve
When does the generator potential occur? in the postsynaptic regions
What does a generator potential do? it allows localized infusion of Na+ and when it is high enough (and nerve threshold is reached) it will generate the action potential
What type of response does a generator potential have? a graduated response to a neurotransmitter
What can change the permeability of a cell membrane? an adequate stimulus
What does a change in permeability allow for? sodium to flow into the cell
What does the change in permeability cause? depolarization
What happens if the change in permeability does not meet the threshold? no action potential will occur
What happens in depolarization? the potential difference changes from a negative value to a positive value
What happens if depolarization leads to a sufficient increase in potential voltage? an action potential will occur
What can an action potential act as? a neural signal
What is another name for hyperpolarization? repolarization
When does hyperpolarization occur? as the ions move toward the resting (more negative) state
When does sodium stop flowing from the cell? when resting potential is reached
What is the absolute refractory period of the nerve impulse? the time between the peak of the action potential and point in time for the most negative potential
What happens during the absolute refractory period? no new discharge can occur
What is the relative refractory period? the time between the most negative potential and the reinitialization of the resting state
What happens during the relative refractory period? it is difficult but possible for a new discharge to occur
What changes the electrical polarity of the cell during basic chemo-electrical activity? the cell membrane becoming more permeable to Na+
How do changes in the electrical activity of the cell during basic chemo-electrical activity move? from the first axon to the cell body and then to the second axon
What happens to the voltage when sodium rushes in? it increases
What does a resting potential result in? a more positive charge outside the cell and a more negative charge inside the cell
What is the beginning of the generator potential? when glutamate causes the ligand-gated channels to open
What happens if the generator potential is large enough? the voltage-gated channels will open to allow the flow of Na+ into the cell and the flow of K+ out of the cell, occurring one segment at a time
How does sodium get into the cell? it penetrates the cell membrane through the nodes of ranvier
What happens due to the rate of sodium penetration being constant? the speed of impulse (ex. nerve conduction rate) is determined by the distance between the nodes of ranvier
How does the distance between the nodes on the 8th nerve compare to others? the distance on the 8th nerve is relatively far compared to others
What is implied by the farther distance of the nodes of Ranvier on the 8th nerve? a faster transmission rate
What happens whent he impulse reaches the terminal arbor? the neurotransmitter is released, which stimulates the dendrites of the next nerve in order
What must happen after the cell is infused with sodium? it must also be removed from the cell as the impulse proceeds from dendrites to the terminal arbor
When is sodium removed from the cell? progressively behind the impulse
Once an action potential beings... it is unstoppable
As the impulse of an action potential moves to the next segment of axons, what happens behind it? areas pump out Na+ in order to return to a negative charge
When is the cell in its resting potential? after all Na+ has been removed from the cell and the interior has its original negative charge
When is the cell ready to fire at a normal threshold? after it returns to its original state
What are the sequence of events for basic chemo-electrical activity? resting potential, generator potential, action potential, absolute refractory, relative refractory, resting potential
What stages of basic chemo-electrical activity need higher levels of stimulation? generator potential and resting potential
What are individual neurons more responsive to? specific frequencies
What can each neuron, no matter their specific frequencies, respond to? a range of frequencies depending on the level of stimulus (neural tuning curve and the upward spread of masking)
What is a phase-lock? a range of frequencies that a neuron can respond to depending on the level of the stimulus
Created by: hrshook0104
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