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Physio Psych Exam 2
Drugs and Substance Use Disorder and Research Methods
Term | Definition |
---|---|
Drug of Abuse | Any psychoactive substance that has the potential for problematic use, often resulting from effects on mood and behavior |
Substance (drug) use | Taking a substance |
Substance (drug) abuse | Continued use of a substance despite negative consequences, development of dependance, presence of withdrawal symptoms, inability to stop, etc |
Drugs of abuse affect what pathway | Mesolimbic pathway |
Side effects of binge/intoxication | rapid increase in dopamine transmission in the mesolimbic dopamine system. |
Withdrawal | Hypo-activity of mesolimbic dopamine system. |
Craving Stage | Preoccupation with obtaining and taking the drug |
Psychoactive Drugs | Any drug that has an affect on the brain, which can alter mood, consciousness, perceptions, and sensations, motor control. |
CT Scan | repeated x-rays to provide a series of horizontal structural images of the brain. |
MRI | Strong magnetic field used to get a detailed structural view of the brain |
DTI | Uses the movement of water through the brain to form a structural view of white matter tracks in the brain. |
EEG | Non-invasive technique where electrodes are positioned around the skull and the electric activity of large populations of neurons is recorded. |
PET Scans | Radioactive compound is injected into the bloodstream of the patient, The scanner then picks up radio emissions from the labeled molecule to measure function. |
Functional MRI | (fmri) combines structural mri with measures of blood oxygen level dependent (BOLD) contrast. Used to measure functional brain activity |
If both twins are diagnosed with the same disorder... | Concordent |
If both twins are diagnosed with the different disorder... | Discordant |
Optogenetics | Can be used to probe neural circuits underlying specific behaviors. |