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Teratology
Alcohol and Street Drugs
| Question | Answer |
|---|---|
| Inheritance of addition: Male children to develop alcoholism | 25% risk |
| Inheritance of addition: Female children to develop alcoholism | 5-10% risk |
| How many children each year are born with FAS in the US? | 4000 |
| Two methods to screen pregnant women for alcohol use... | 1. Laboratory tests 2. Brief questionnaires |
| 4 P's for assessment of risk drinking | Pregnancy, Past, Partner, Parents |
| NET | Normal drinker? Do you ever have an EYE-opener? How many drinks does it TAKE to make you feel high? |
| Laboratory tests for disk drinking | liver damage, increased MCV, urine toxicology |
| Alcohol can lead to... | Pregnancy loss, FAS (Growth retardation, CNS dysfunction, facial features, malformations) |
| CNS abnormalities with FAS | below average intelligence, hyperactivity, attention deficits, language dysfunction, perceptual difficulties |
| Tobacco... increased risk for | IUGR, prematurity, stillbirth; facial clefts, learning disorders, hyperactivitiy, |
| Postnatal exposure to Tobacco... | SIDS, asthma, ear infections |
| The possibility of substance abuse must be considered in ... | ALL pregnant women. |
| Cocaine and pregnancy... | vasoconstrictive and hypertensive activity ; OB complications ; IUGR, small risk for malformations (GI, cardiovascular) |
| Cocaine... | neonatal behavioral abnormalities (disappear in the first few months of life), long term impact on cognition and behavior not well understood; SIDS; |
| When cocaine is excreted in breast milk... | reports of vomiting, tremulousness, irritability, and seizures |
| Marijuana.... what is excreted in breastmilk? | THC |
| Some evidence that marijuana causes... | behavioral changes |
| Marijuana use in the 3rd trimester can cause... | adaptation syndrome |
| Amphetamines & studies | animal & human studies are inconsistent |
| Amphetamines & 3rd trimester use... | low birth wt, prematurity, withdrawal symptoms, possible long term effect on cognition and behavior |
| LSD (prior use, chromosomal damage?) | Not associated with increased risk for abnormalities in subsequent pregnancies and does not appear to cause chromosome damage |
| LSD case reports of ... | CNS, eyes, limbs, not most studies have not substantiated this |
| Heroin | long term behavioral abnormalities, increased risk for OB complications including IUGR, prematurity, fetal distress, perinatal mortality, SIDS, neonatal withdrawal |
| Inhalation of solvents | fetal damage similar to that seen with FAS (preterm labor, growth deficiency, microcephaly and CNS dysfunction, facial features) |
Created by:
KChatham
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