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Micro Anaerobes
Micro Anerobes
| Question | Answer |
|---|---|
| Only NON-MOTILE Clostridium Species. | perfringens |
| Gram positive bacillus that are BOXCAR shaped. | C. perfringens |
| When plated with S. aureus, this species performs a REVERSE CAMP (blunt ends)on SBA. | C. perfringens |
| This species causes GANGRENE. | C. perfringens |
| This species has terminal spores that look like DRUMSTICKS. | C. tentani |
| This species causes TETANUS or "LOCKJAW" | C. tentani |
| What two toxins does C. tetani have? | Tetanolysis and Tetanoplasmin |
| This species has endospores that look like TENNIS RACKETS. | C. botulinum |
| Jarred jellies and processed meats can cause this toxin | Botulism |
| A and B enterotoxins are found in this species. | C. difficile |
| On CCFA media, these colonies turn yellow. | C. difficile |
| This species has a SAFETYPIN appearence. | Bacteroides fragilis |
| Spindle shaped morphology that is common in respiratory and GI tract. | Fusobacterium Sp. |
| Causes lung and dental infections | Prevotella melaninogenica |
| Grows black pigmented colonies | Prevotella melaninogenica |
| Causes purple pigmented agar | Porphyromonas |
| "Anaerobic Staph" | Peptococcus |
| "Anaerobic Strep" | Peptostreptococcus |
| Rapid ID ANA remel, API 20 1 biomerieux,and BBL crystal ANA ID are examples of... | Biochemical System testing |
| Darkfield and Westernblot | Are other ways to ID anaerobes |
| tightly coiled Helix that have spiral rotations | Leptospira interrogans |
| Reservoir of cat, dog and rats | Leptospira interrogans |
| Causes LYME disease | Borriela burgdorferi |
| What species of tick causes Lyme disease | Ixodes |
| Causes the "BULLS EYE RASH" | Borriela burgdorferi |
| Pediculus humanus (human louse) | Borriela recurrentis |
| Soft tick species that causes B. hermsii, B. parkeri, B. turicatae | Ornithodoros |
| This species cause SYPHILIS | Treponema pallidum |
| Latent syphilis causes | reappearence of lesions |
| Tetiary syphilis causes | Tissue damage |
| Congenital syphilis causes | baby infections |
| Hutchinsons teeth | Treponema pallidum |
| "ROCKY MOUNTAIN SPOTTED FEVER" | Rickettsiae |
| This species must be cultured on "non artifical media" | Rickettsiae |
| The species first appears with a RASH on ANKLES and WRISTS | Rickettsiae |
| Catch from Cat and Rat fleas | Typhus |
| What test can be used to determine typhus | Weil Felix test |
| STD, and cause eye infections | Chlamydia trachomatis |
| Linked to coronary heart disease and is a human infection only | Chlymydia pneumoniae |
| Causes "PARROT FEVER" | Clamydia psittaci |
| Tissue culture | McCoy cells |
| Detects outer membrane | DFA-Direct Florescent Antibodies |
| Positive PPD | Tuberculosis mycobacterium |
| PPD stands for | Purified Protein Derivative |
| Nitrate and Catalase Positive | TB |
| Found in AIDS patients and is similar to TB | Mycobacterium avium (MAC) |
| On photochromogen, this species is non pigmented in dark and yellow in light | Mycobacterium kansasii |
| Causes skin and soft tissue disease | Mycobacterium fortuitum |
| Hansens Disease | Mycobacterium leprae |
| LEPROSY is caused by | Mycobacterium laprae |
| Tuberculoid | skin lesions |
| Lepromatous | cartlidge distruction |
| Fish disease | Mycobacterium marinum |
| Causes cervical lymphadentitis | Mycobacterium scrofulaceum |
| Smooth buttery colonies | Mycobacterium scroflaceum |
| Found in water taps and soil | Mycobacterium gordonae |
| grows in 10-14 days and has smooth yellow/orange colonies | Mycobacterium gordonae |
| High risk in crowded areas (shelters, schools, etc.) | Mycoplasma pneumoniae |
| WALKING PNEUMONIAE | mycoplasma pneumoniae |
| "FRIED EGG" appearence on PPLO agar | Mycoplasma pneumoniae |
| Genital tract ulcers | mycoplasma hominis |
| STD of "MALES" | Ureaplasma urealyticum |
| Detected by Rapid mycoplashea test | Uraplasma urealyticum |
| Ureaplasma splits | urea |
| Kills directly | bactericidal |
| Prevents growth | bacteriostatic |
| Artifical | Synthetic |
| Chemically altered | semi-synthetic |
| Antibiotic killing normal flora turns infection into... | Super Infection |
| Enzymes for synthesis | peptidoglycan |
| Prevents cell wall synthesis | beta lactam |
| Used on grm positive and gram negative cocci | Penicillin |
| Good for gram positive, modest against gram negative | first generation cephalosorins |
| better action again gram negative b/c stable against beta lactamases | second generation cephalosporins |
| less activity against gram positives but better against enterics | third generation cephalosporins |
| acts against aerobic gram negative rods (p. aeruginosa) | Monobactam |
| Broad spectrum of any microbial agaent | Carbapenem |
| Combination with this drug can be synergistic | beta lactem |
| Works only against Gram positive organisms | Vancomycin |
| These are toxic when used as topical antibiotics | Bacitracin and cycloserine |
| What commonly used topical antibiotic has Bacitracin | Neospren |
| alters permeability and osmotic integrity | Polymyxins |
| Binds IRREVERSIBLY to 30S ribosomal unit | Aminoglycosides |
| Binds REVERSIBLY to 30S ribosomal unit | Tetracyclines |
| IV antibiotics must be administered in the hospital due to,,, | Blood brain barrier cross over |
| Effects bacterial replication | Sulfonamides |
| Sulfonamides such as RIFAMPIN is used specifically for | Mycobacterium |
| Interfere with DNA synthesis by making DNA ineffective | Nalidixic acid and Quinolones |
| Disk Diffusion Method | Kirby Bauer |
| Bacterial suspension containing 1.5 x 10*8 CFU/ml | McFarland Standard |
| Cation concentration on agar is important due to Mg and Ca | Mueller-Hinton agar |
| Lowest concentration of antimicrobial agent required to inhibit visible growth | Minimal Inhibitory Concentration (MIC) |
| Lowest concentration of antibiotic that kills 99.9% growth | Minimal Bactericidal concentration (MBC) |
| Must be drawn 15 min before dose | Trough |
| Must be drawn 30-60 min after dose given | Peak |
| Strip impregnated with antibiotics with scale for measurment | E test |