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Receptors

TermDefinition
Receptor
Protein in either the plasma membrane or the interior of a target cell that a chemical messenger binds with
Specificity Bind to only one type or limited number of structurally related types of chemical messenger
Saturation Receptors are occupied by messengers. If all are occupied the receptors are fully saturated; if half are occupied the saturation is 50%
Affinity Strength with which a chemical messenger binds to its receptor
Competition Compete with a ligand for binding to its receptor
Antagonist A molecule that competes with a ligand for binding to its receptor but does not activate signaling normally associated with the natural ligand. (Stimulates receptor)
Agonist Often refers to a drug that mimics a normal messengers action. (Blocks body response)
Down-regulation Decrease in the total number of target-cell receptors for a given messenger. Use when they are over stimulated. High ECF concentration
Up-regulation Increase in the total number of target cell receptor for a given messenger. Help the cell get stimulated. Low ECF concentration
Increased sensitivity Responsiveness of a target cell to a given messenger
Created by: Angelica P
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