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Leukopoiesis
Study for WBC test
| Question | Answer |
|---|---|
| What granulocyte has rose-violet granules? | Neutrophils |
| What percent Neutrophils will you see of the WBCs in peripheral blood? | 50-70% |
| What granulocyte phagocytize bacteria? | Neutrophils |
| What WBC is considered the garbage disposal? | Mononcyte |
| What percent Eosinophils will you see of the WBCs in peripheral blood? | 1-3% |
| What percent Basophils will you see of the WBCs in peripheral blood? | 0-1% |
| What percent Lymphocytes will you see of the WBCs in peripheral blood? | 20-45% |
| What percent Monocytes will you see of the WBCs in peripheral blood? | 2-11% |
| What is a normal WBC count in peripheral blood? | 5000-10,000 |
| Where do T Lymphocytes go when they leave the bone marrow? | Thymus |
| What lymphocyte produces antigens and are the recognizer cells? | T lymphs |
| What lymphoctes produce antibodies? | B lymphs |
| What WBC is considered the yard stick when looking at a blood smear? | Mature lymphs |
| What WBC is large with an irreguarly shaped nucleus and ground glass cytoplasm? | Monocyte |
| What is used to identify very young WBCs? | Cell markers |
| What cell markers are associated with young lymphocytes? | TdT and calla. (also CD4 and CD8 but I think the first two will suffice. |
| What cell markers are associated with young neutrophils? | CD33, CD13 and CD34. CD34 falls off early. |
| At what stage of maturation do the primary granules appear? | Promyelocyte |
| At what stage of maturation do the secondary or specific granules appear? | Myelocyte |
| What percent Bands will you see of the WBCs in peripheral blood? | 5-7% |
| What WBC will increase in the presents of a bacterial infection? | Neutrophils |
| What WBC will increase in the presents of a viral infection? | Lymphs |
| What granulocyte will respond to allergies or parasites? | Eosinophils |
| What granulocyte might cause anaphlaxis or hemorrhage? | Basohpils |
| What do Eosinophil granules contain? | Antihistamine |
| What do Basophil granules contain? | Histamine and heparin. |
| What do Basophils become in the tissue? | Mast cells |
| What do Monocytes become in the tissue? | Macrophages |
| What granulocyte has primary granules containing myeloperoxidase? | Neutrophils |
| What granulocyte has secondary granules containing LAP and lysozyme? | Neutrophils |
| Name the stages of granulocyte maturation. | Myeloblast, Promyelocyte, Myelocyte, Metamyelocyte, Band, and Seg. |
| Name the stages of Monocyte maturation. | Monoblast,Promonocyte, Monocyte |
| Name the stages of Lymphocyte maturation. | Lymphoblast, Prolymphocyte, Lymphocyte |
| At what stage do we see the "Dawn of Neutrophilia?" | Myelocyte |
| What is the last stage that a granulocyte can proliferate? | Meylocyte (pretty sure) |
| What granules will be forming at the "Dawn of Neutrophilia?" | Secondary or specific |
| What lymphocyte becomes a plasma cell? | B Lymph |
| I count 4 WBC pools, name them. | Bone marrow, circulating, marginating,and tissue |
| In relation to this unit, what cells should be found in the spleen? | Lymphocytes |
| What happens to the thymus as a child grows into an adult? | It shrinks |
| What is the rarest of granulocytes? | Basophils |
| At what stage of granulocyte maturation might you see nucleoli fading? | Promyelocyte |
| At what stage of granulocyte maturation might the nucleus be round to oval and flattened on one side? | Myelocyte |
| At what stage of granulocyte maturation might the nucleus be kidney bean shaped? | Metamyelocyte |
| At what stage of granulocyte maturation might the nucleus sides be parallel? | Band |
| At what stage of granulocyte maturation might the nucleus be segmented? ;-) | Seg |
| What cell has Robin's Egg Blue cytoplasm? | Lymphocyte |
| What is probably the largest WBC that you will see in peripheral blood? | Monocyte |
| At what stage of granulocyte maturation will you see fillaments? | Segs |
| What is diapedesis? | The putting out of a foot of a neutrophil to squeeze through the blood vessel wall. |
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