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inflammatory mediato

major pro-inflammatory mediators

TermDefinition
tumor necrosis factor-alpha fever, lack of appetite
interleukins fever, platelet production, fatigue, anemia, headache
histamine vasodilation, increases vascular permeability, activates endothelium
kinins increases vascular permeability, smooth muscle contraction, pain, natriuresis, hypotension
platelet-activating factor vasodilation, increases vascular permeability, platelet aggregation, angiogenesis, leukocyte adhesion to endothelium
prostaglandins pain, fever, vasodilation, muscle spasm
leukotrienes bronchospasm, increased vascular permeability
substance P pain, hypotension, enhances vascular permeability
Created by: elenafranco
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