Busy. Please wait.
Log in with Clever

show password
Forgot Password?

Don't have an account?  Sign up 
Sign up using Clever

Username is available taken
show password

Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Didn't know it?
click below
Knew it?
click below
Don't Know
Remaining cards (0)
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Block 6-Urea

Block 6- Urea cycle

Where is urea synthesized? liver
What is the structure of urea? 2 amino groups attached to a central carbonyl group
Where do the parts of urea come from? Carbonyl derived from CO2, 1 N-atom from aspartate (asp) the other from ammonium
Where does Urea synthesis begin and end within the cell? Mitochondria to start, cytoplasm to finish
How much energy is required to run the urea cycle? 4 ATPs
What is the crucial, rate limiting first enzyme for urea synthesis (found in mitochondria)? carbamoyl phosphate
What is the second enzyme of the urea cycle? Also rate limiting Ornithine transcarbamoylase condenses carbamoyl phosphate with ornithine to form citruline
The most common genetic defiencies in urea cycle are associated with what? the two enzymes: carbamoyl phosphate & ornithine transcarbamoylase
What does arginase do in the urea cycle? Where? cleaves arginine into urea and ornithine (which is recycled.
Where does apspartate occur in the urea cycle? It enters in the cytoplasm to convert citrulline to argininosuccinate which cleaves to form fumarate and arginine by a lyase.
Is all the arginine required available via urea synthesis? No, most comes from diet.
What happens with CPS-1 and Ornithine transcarbamoylase deficiency? Hyperammonenemia; Decrease in BUN (Blood Urea Nitrogen, Cerebral edema;lethargy, convulsion, coma, death
What is the difference between Aspartate and Fumarate? fumarate does not have the amino group
Where does fumarate go following the urea cycle? It can enter the TCA for energy or gluconeogenesis
Where does urea go from the kidney? Transported by blood to the kidney
What is the famous phrase regarding the urea cycle? Better to be pissed off, than pissed on
Created by: El Diablo
Popular Biochemistry sets




Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!
"Know" box contains:
Time elapsed:
restart all cards