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VET 201- Exotic Lab
Facility Design/Equipment/Housing/Management
| Term | Definition |
|---|---|
| Corridor Length | 6-8 feet |
| Door Size | 42" x 84" |
| Air Changes/Hour | 10-15 air changes per hour |
| Ventilation | use of air pressure differentials and/or high efficiency particulate air (HEPA) filters are recommended to control cross-contamination. |
| Negative Pressure | this type of air pressure should be used for quarantine, isolation, and housing of nonhuman primates. This pressure is relative to the corridor/anteroom |
| Anteroom | an antechamber, typically serving as a waiting room. |
| Positive Pressure | this type of air pressure should be used for surgery and housing pathogen-free animals. |
| Biosecurity | degree of protection required from adventitious infectious agents and/or experimentally induced contagions needs to be considered. |
| Single Corridor System | unidirectional traffic flow or bidirectional traffic flow. |
| Dual Corridor System | designated clean and soiled corridor, minimizes cross-contamination within facility. |
| Negative Pressure Rooms | kept at a pressure less than the surrounding rooms, more air is pumped out than in, air moves in when door is opened, helps keep airborne contaminates from escaping the room. Not noticeable to staff. |
| Positive Pressure Rooms | kept at a pressure greater than surrounding rooms, air moves out. Helps to prevent outside contaminants from entering. |
| Barrier Rooms | rooms designed to prevent entry of disease into a room (bioexclusion) OR to prevent disease inside a room from getting out (biocontainment). |
| Containment/Biohazard Facilities | these facilities protect the general animal/human population by minimizing the potential escape of experimentally induced contagions, access is restricted. |
| Biohazard PPE | this is dictated by the Animal Biosafety Level designation of the room/area. Includes: N95 respiratory, disposable gowns/surgical cap, positive pressure ventilated suits w attached boots. |
| Biohazard Equipment | these are treated with autoclaves, incinerators, and air filters before they leave the facility. |
| Rack Cage Washer | used to sanitize large pieces of equipment |
| Cabinet Cage Washer | smaller version of the rack washer, constructed in configuration of a large cabinet. |
| Tunnel Cage Washer | equipment/caging carrier through various stations on a conveyor belt, sanitized items exit the opposite side of the tunnel. |
| Sanitation Temp | 180*F |
| Sanitation | reduction of the number of microorganisms on object to an acceptable public health standard. |
| Disinfection | a process that destroys pathogenic microorganisms or inhibits their growth. |
| Sterilization | destruction of all organisms on an object. |
| RODAC Plate Testing | measures bacterial colonies remaining on sanitized equipment |
| ATP Bioluminescent Technology | measures the presence of adenosine triphosphate, molecule present in all living organisms. |
| Automatic Watering Systems | reduces efficiency issues inherent in bottle handling, less labor intensive, must be periodically sanitized by flushing system, filters and pressure regulators need to be replaces at established intervals. |
| Bottles w/ Sipper Tubes | water method commonly utilized, presents efficiency issues and is labor intensive. Used when water needs to be monitored or measured or when medications or compounds need to be given. |
| Sipper Sacks/Hydrogel Packs | water method useful when transporting or shipping rodents. |
| Dry Pelleted Foods | food that can be used up to 6 months after manufacture |
| Purified/Chemically Defined Diets | diet stored at 390*F or lower, less stable than natural-ingredient diets, shelf live may be less than 6 months. |
| Autoclavable/Irradiated Diets | diet adjusted in nutrient concentrations and ingredients to ensure adequate nutritional level, date of sterilization should be recorded on autoclaved package. |
| Perishable Foods | diet stored in the refrigerator, utilized quickly for product freshness. |
| PuriCare Bedding Disposal Station | bedding disposal station that protects operator from airborne particles. Room air is drawn in the from and then 100% of the air passes through a filter to trap large particles. |
| Acceptable Caging | allows for normal physiological and behavioral needs of the animals. For breeding, cages should provide for the animals' space and physical requirements for reproduction. |
| Polystyrene Cages | disposable material, intended for use with biohazard or chemical hazard protocols. |
| Polypropylene Cages | opaque material, provide breeding animals more seclusion. |
| Polycarbonate Cages | clear, high-impact strength material. It has an autoclavable version that's used for protocols which require sterile caging. |
| Polyphenylsulfone Cages | material that comes in a variety of clear colors, can withstand over 2,000 autoclaving cycles. |
| Microisolation System | a refinement of the shoebox cage system. Allows for greater control of the cage environment, has a filtered plastic top. Can be static (without forced ventilation) or ventilated. |
| Isolator | a chamber made of clear plastic material kept under positive pressure. Workers manipulate items by using sleeved gloves sealed to ports, provides a sterile environment. |
| Individually Ventilated Cages (IVCs) | a refinement to static microisolation caging system, constructed w a port and docking system. Has automatic watering (via lixit) and continuous airflow. Allows less ammonia and carbon dioxide levels. |
| Suspended Cages | cage that hands from an aluminum or stainless steel runner built into a mobile rack, has a perforated/wire mesh flooring. Allows waste to drop through to a collection pan beneath. |
| Space Recommendations | these are recommendations that are located in the Animal Welfare Act and The Guide. |
| Front-Opening Cages | cages used for rabbits, ferrets, and chinchillas. provides front access to the animal. |
| Metabolism Cages | cages used in studies where urine/feces collection is required. Has funnel-like apparatus under cage to separate feces and urine. Drinking (SLIDE 55) |
| Exercise Cages | |
| Group/Gang Cages | |
| Nonhuman Primate Caging | |
| Squeeze Cages | |
| Transport Cages | |
| Operating Funds | |
| Recordkeeping | |
| Management | |
| Euthanasia in Research | |
| AVMA Guidelines on Euths | |
| Euth Methods | |
| Training | |
| Laboratory Animal Allergies (LAA) | |
| Water Treatment Methods | -filtration, UV lighting, hyperchlorination, reverse osmosis, autoclaving. |
| Shoebox-Style Cage | commonly used caging, made of plastic and has a stainless steel V-shaped lid to hold food and water. |
Created by:
Riley.Scherf
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