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VET 201- Exotic Lab

Guinea Pig

TermDefinition
Guinea Pig (Cavia procellus) rodent related to chinchillas and porcupines, known as cavy/cavies, originated from Andes mountains, South America.
English Guinea Pig pig with short straight hair. Has outbred, inbred, and mutant strains.
Abyssinian Guinea Pig pig with short course hair arranged in whorls.
Peruvian Guinea Pig pig with long fine silky hair.
Guinea Pig Uses -food source in South America, research
Behavior -communal, male-dominated social hierarchies, huddle next to side of cage, barbering when bored or for dominance, active during day and night, waste food, vocal.
Dental Formula 2 (I 1/1, C 0/0, P 1/1, M 3/3) all teeth are open rooted
Coprophagic involving the eating of excrement
Sebaceous Marking Glands glands located near the rump, pigs will walk or sit while pressing these glands against a surface.
Male Guinea Pigs larger in size, has large testes and an os penis with two prongs at tip. Has slit-shaped rectal opening and several accessory sex glands. Penis can be felt under the skin and protruded by manual pressure.
Anogenital Distance very little difference in distance.
Female Guinea Pigs bred at 2-3 months of age or 350-450 g. May double in weight during pregnancy. Need to be bred prior to 7 months to prevent permanent fusion of pelvic symphysis.
Estrus continuously polyestrous, has a 15-17 day estrous cycle.
Gestation 59-72 (68) days. Sow does not build a nest.
Farrowing usually takes 30 minutes, with 5-10 minutes between pups. Has 1-6 pups. Are fertile postpartum and estrus occurs 2-10 hours after birth.
Young Guinea Pigs
Diet should be fed ad libitum, do not feed rabbit food, use self-feeders hung on wall. Need kale, parsley, beet greens, kiwi fruit, broccoli, oranges, cabbage for Vitamin C.
Small Blood Collection pigs lack readily accessible peripheral veins. Small amounts under 1 mL can use a saphenous or cephalic vein.
Large Blood Collection Large quantities of blood use a cranial vena cava or jugular vein, or femoral vessels under sedation. Cardiac can also be used under anesthesia.
Urine Collection -digital pressure on bladder, cystocentesis, metabolic cage.
Oral Drug Admin. this is done by using a small oral syringe. The anatomy of the soft palate makes it difficult to use a feeding tube.
Subcutaneous Drug Admin. this is done over the neck and back, skin tends to be tough.
Intramuscular Drug Admin. this is done in the lumbar or quadriceps muscles used to avoid injury to the sciatic nerve.
Intraperitoneal Drug Admin. injections in this are made lateral to the midline in the lower right quadrant.
IV Drug Admin. this is done in a saphenous or cephalic vein.
Anesthesia should not be fasted for 3-6 priors to induction. Care must be taken to determine true body weight. Eye lubricant and supplemental heat are important during anesthesia.
Surgery pigs can be difficult to monitor since inhalant agents can cause animal to show squirming movements although they are not conscious. Ear pinch/resp rate/heart rate are more reliable.
Symptoms of Pain -abnormal posture appearing hunched, excessive salivation, reluctance to move.
Euthanasia Methods -inhalant anesthetic overdose -IV/IP admin of euth agent -overdose of injectable anesthetic agent -exposure to controlled release of carbon dioxide
Illness Signs -hunched posture, scruffy unkempt coat, reduced appetite and weight loss, lethargy, disinterest in surroundings, discharge from eyes/nose, diarrhea.
Antibiotic Toxicity guinea pigs are highly sensitive to antibiotics, normal flora is destroyed and permits an overgrowth of gram-negative organisms. Disease is almost always fatal.
Bordetella bronchiseptica and Streptococcus pneumoniae younger/pregnant sows at risk. Affected animals have no clinical signs of these. Signs may include: dyspnea, nasal discharge, sneezing, anorexia, ruffled fur.
Salmonellosis a highly lethal bacterial disease, rarely detected in research facilities. Mainly from contaminated water/food.
Ulcerative Pododermatitis commonly called bumblefoot, frequently associated with Staphlococcus spp. infection. Obese animals and animals w/ wire flooring are susceptible.
Mastitis common bacterial disease in lactating sows. Glands become warm, enlarged, and hyperemic. Young should be weaned immediately if sow is infected. Treated w/ systemic antibiotics/analgesics, hot packs may also help.
Conjunctivitis chlamydophila caviae causes this. Outbreaks are common in enzootically infected colonies. Adults are usually asymptomatic. Overt signs of disease seen in 1-3 wk old pigs.
Cystitis and Urolithiasis UTIs are common in older sows. Disease often subclinical until blockage or severe infection occurs. Commonly treated w/ trimethoprim-sulfa or enrofloxacin. Urinary calculi are common.
Dermatophytosis
Cytomegalovirus (CMV)
Adenovirus
Acariasis
T. caviae
C. caviae
Protozoans
Cryptosporidium wrairi
Nematode Infections
Neoplasia
Trauma
Heat Stress
Scurvy
Preputial Infection
Vaginitis
Dystocia
Pregnancy Toxemia
Gastric Dilation, Cecal Torsion, and Typhilitis
Diabetes Mellitus
Soft Tissue Calcification
Osteoarthritis
Created by: Riley.Scherf
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