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PMI A&P Ch3
PMI Anatomy & Physiology Ch3
| Question | Answer |
|---|---|
| cells | size and shape; human cells vary considerably in size; all are microscopic; cells different notably in shape |
| cytoplasm | fluid in which all the organelles are in |
| organelles | specialized structures within the cytoplasm |
| plasma membrane | forms outer boundary of cell; composed of a thin, two-layered membrane of phospholipids containing proteins; is selectively permeable |
| ribosomes | may attach to rough endoplasmic reticulum (ER) or lie in cytoplasm; made of two tiny subunits of mostly ribosomal RNA; manufacture enzymes and other protein compounds; often called the protein factories |
| endoplasmic reticulum (ER) | network of connectiong sac and canals; carry substances through fluid cytoplasm; |
| golgi apparatus | group of flattened sac near the nucleus; collect chemicals into vesicles that move from the smooth |
| mitochondria | composed of inner and outer membrane sacs; involved with energy-releasing chemical reactions; contains one DNA molecule; ATP |
| lysosomes | membraneous-walled organelles; contain digestive enzymes; have a protective function (eat microbes); formerly thought to be responsible for apoptosis (programmed cell death) |
| centrosome | region od cytoplasm near nucleus; serves as microtubule-organizing center of cell; centrioles found within centrosome; paired organelles that lie at right angles to each other neat the nucleus; function in cell reproduction |
| microvilli* | cell extension; small, fingerlike extension |
| flagella | single projections extending from cell surfaces; much larger than cilia |
| nucleus | surrounded by nuclear envelope; made up of two separate membranes; contains nuclear pores; contains nucleolus |
| chromatin | unwound DNA; found throughout interphase; DNA is being used for macromolecule synthesis |
| chromosomes* | tightly packaged DNA; |
| relationship of cell structure and function | every human cell has a designated function; some help maintain the cell; others regulate life processes of the body itself; specialized functions of the cell differential depending on the number and the number and type of organelles |
| passive transport | does not require added energy; result in movement "down a concentration gradient" |
| diffusion | substances scatter themselves evenly throughout an available space; it is unnecessary to add energy to the system; movement is from high to low concentration |
| osmosis | diffusion of water (when some solutes cannot cross the membrane); substance always tries to equalize itself |
| dialysis | diffusion of solutes; concentration |
| filtration | movement of water and solutes caused by hydrostatic pressure on one side of membrane; responsible for urine formation |
| active transport process* | occurs only in living cells; movement of substances is "up the concentration |
| ion pumps | a protein complex in the cell membrane; ion pumps use energy from ATP to move substances across cell membranes against their concentration gradients; example: sodium-potassium pump and calcium pump; some work with other carries |
| phagocytosis | a protective mechanism often used to destroy bacteria |
| pinocytosis | used to incorporate fluids or dissolved substances into cells |
| phagocytosis and pinocytosis | both are active transport mechanisms because the require cell energy |
| cystic fibrosis | characterized by abnormally thick secretions in the airways and digestive ducts, results from failed Cl- (chloride ion) transport |
| cholera | a bacteria infection that causes Cl- and water to leak from cells lining the intestines, resulting in severe diarrhea and water loss |
| cell growth and reproduction | DNA molecule resembles a long, narrow ladder twisted round and round its axis; shaped in a double helix; each molecule is made of a sugar (deoxyribose), bases, and phosphate units; bases are nitrogen-containing chemicals: adenine,thymine,guanine,&cytosine |
| AT | adenine attached to thymine |
| GC | cytosine attaches to guanine |
| DNA | complementary base pairing: each step of DNA ladder contains a base pair; adenine-thymine or cystonine-guanine; a gene is specific segment of base pairs in a chromosome |
| DNA location | nucleus of the cell |
| protein synthesis | occurs in the cytoplasm of the cell, thus genetic information must pass from the nucleus to the cytoplasm |
| transcription* | making a copy of the blueprint; double-stranded DNA separates to form messenger RNA (mRNA); each strand of mRNA duplicates a particular gene )base |
| translation | involves synthesis of proteins in cytoplasm by ribosomes; requires use of information contained in mRNA; codon: series of three nucleotide bases that ace as a code for a specific amino acid |
| abnormal DNA | is inherited, or that results from damage, is often the basis of disease |
| factors that cause damage to DNA molecules | chemical or mechanical irritant, radiation, bacteria, and viruses |
| **mutagenic substances we are exposed to in the OR | ** |
| *DNA replication | process by which each half of a DNA molecule becomes a whole molecule |
| mitosis | process in cell division that distributes identical chromosomes into each of the new cells formed when the original cell divides |
| prophase | first stage; chromatin granules become organized; chromosomes appear; centrioles move away from nucleus; nuclear envelope disappears, freeing genetic material; spindle fibers appear |
| metaphase | second phase; chromosomes align across center of cell; spindle fibers attach themselves to each chromatid |
| anaphase | third stage; centromeres break apart; separated chromatids no called chromosomes; chromosomes are pulled to opposite sides of the cell; cleavage furrow develops at end of anaphase |
| *telophase | fourth stage; last stage; cell division is completed; nuclei appear in daughter cells; nuclear envelope and nucleoli appears; cytoplasm is divided (cytokinesis) |
| hypertrophy | increase in size of individual cell; increasing size of tissue |
| atrophy | decrease in size of individual cells; decreasing size of tissue |
| hyperplasia | increase in cell reproduction, increase size of tissue |
| anaplasia | production of abnormal, undifferentiated cells |
| benign cancer | encapsulated in one area; can still grow but can not go to different tissues |