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Hematology
Advanced Patho
| Question | Answer |
|---|---|
| What does most of our bodies iron come from | Recycling old RBCs |
| what is the MCHC | the average HBG in a single RBC |
| What anemias happen with a normal MCHC (normochromic) | aplastic, post hemmorhagic, hemolytic |
| What anemias happen with a low MCHC (hypochormic) | iron def, sideroblastic, thalessemia, |
| What anemias happen with a high MCHC (hyperchrmoic) | liver disfuction, hyperthyroid ad sickle cell, |
| What is iron deficiency | Mircocytic and hypochromic |
| Iron defiiciency has which low lab value | ferritin |
| What is RDW | the red blood cell distribution width |
| What does RDW determine | Macro, micro or normo cytic |
| Who is at risk for being folate deficient | ETOH |
| What type of anemia does folate deficiency cause | Megaloblastic |
| What are the s/s of vit b 12 def | fatigue, dyspnea and perpherial neuropathy |
| Who is at risk for Vit b12 def | older adult, H-pylor infection |
| Hemolytic anemias from HS2 reactions are | HS2- mixed matched blood type |
| Hemolytic anemias from HS3 reactions are | auto immmune vs erythrocytes |
| Homolytic anemais from HS1 reaction | Drug induced |
| How do you dx aplastic anemia | bone marrow biopsy and blood tests |
| What lab work does aplastic anemia show | granulocytes are less than 500, platelets are less than 20K and reticulocytes are less than or equal to 40x109/L |
| Which anemias are inherited | Sickle cell and thalessemia |
| Which inherited anemias can possess many genetic mutation | Thalessemia |
| Which inherited anemia is passed from at least 1 parent | sickle cell |
| what is a recticuloctyes | immature RBS |
| What is MCV | average size of a RBC |
| What is MCH | average wt of a HBG |
| What is anemia | decreased HBG and RBCs |
| 3 ways anemia can occur | impaired RBC production, acute BL and increase RBC destruction |
| most common type of anemia | iron def anemia |
| Folic acid is essential to the body because | Plays a major role in the maturing of RBCs. |
| Folate and cobalamin (vitamin B12) are required for | red blood cell DNA synthesis |
| lab values will be low in a patient with folate deficiency | Reticulocyte count. |
| Aplastic anemia can be caused by: | abx |
| Which inherited anemia must be passed by both paretns | thalessemia |
| What are the lab values for aplastic anemias | MCV, MCHC normal, reticulocyte is low |
| What are the lab values for post-hem anemias | MCV, MCHC normal, reticulocyte is high |
| Hemolytic anemia lab values | MCV, MCHC normal, reticulocyte is high |
| What is considered microcytic (lab value) | MCV less than 80 |
| What is considered normocytic (lab value) | MCV 80-99 |
| What is considered macrocytic (lab value) | MCV greater than 100 |
| Examples of microcytic anemias | iron def, thalessima, sideroblastic chronic diseas |
| Examples of normocytic anemias | hereditary spherocytosis, anemais of inflammation, |
| examples of macrocytic anemias | b12 def, folate def. |
Created by:
kristengeis
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