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Immune Response
Advanced Patho
| Question | Answer |
|---|---|
| Hypersensitivity 1 is mediated by | IgE |
| HS 1 reaction common reactions | anaphylaxes, local, itching and sneezing, allergic rhinitis |
| treatment for systemic HS 1 reaction | epinepherine |
| What happens in HS 1 reaction | mast cell degranulation |
| What is a HS 1 reaction | allergic reaction |
| What is a HS 2 reaction | cytotoxic reaction |
| What is HS2 mediated by | IgG IgM |
| What does the HS2 do? | causes damage and altered fxn to tissue |
| What is two common reactions with HS2 | Graves and blood incompatibility. |
| Which HS reaction is organ specific | HS2- antibody binds to antigen on the cell surface |
| what HS reaction is not organ specific | HS30 antibody binds to antigen OUTSIDE of cell surface and deposited in tissues from blood |
| What is a HS3 reaction | immune complex reaction |
| What. is the primary effector in HS3 | neutrophils |
| What HS reaction is considered autoimmue | HS3 |
| Two common types of HS3 | RA and Lupus. RA in joints and Lupus throughout body system and can be different |
| What is a HS4 reaction | Cell mediated and delayed reaction |
| What are HS4 primary mediators | T-cell lymphocytes |
| Which HS reaction isnt related to anitbodies | HS4 |
| What is a common HS4 reaction | contact dermatitis |
| Which HS reaction is widely distributed with atopic dermatitis | HS1 |
| Which HS reaction is at the site of contact | HS4 |
| How do you treat atopic dermatitis | antihistimines and epinepherine |
| How do you treat contact dermatitis | oral or topical steroids |
| Which HS reaction is immediate | HS1 |
| Which HS reaction is delayed | HS4 |
| What is autoimmunity | Graves, lupus, RA |
| What immunity has a familial association | Autoimmunity |
| What is alloimunity | immune system reacts to tissue of OTHER member of same species |
| What immunity is is transplant/transfusion reaction | alloimmunity |
| What is primary immunodef | due to a single gene defect, something missing |
| What is an example of primary immunodef | B-lymphocyte deficiency |
| What is secondary immunodef | complication of other physiological condition |
| What is an example of secondary immodef | HIV gets pneumocystits PNA, infection, chemo, |
| What is the most common cause of secondary immodef | Malnutrition |
| What is the first responders of immune system | Neutrophils |
| inflammatory mediators such as histamine, leukotrienes, and prostaglandins do what? | vasodilation, bronchial smooth muscle contraction, and mucus production. |
| what is the primary effector of HS2 | macrophages |
| HS2 reactions | drug allergies, hemolytic anemia, blood transfusion mismatch with resulting transfusion reaction and Rh hemolytic disease. |
| Common HS3 reaction | serum sickness, raynauds |
| What happens in a HS3 reaction | Complex deposited in small peripheral vessels in cool temperatures leading to vasoconstriction and blocked circulation |
| immune components can be involved in autoimmune diseases | T-Cells, B-cells and autoantibodies |
Created by:
kristengeis
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