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Immuno ch 1

Introduction to Immunology

TermDefinition
1. Natural killer cells -Similar to T and B cells -No epitope specific surface receptors of B and T cells (not antigen specific) -larger, granular than B, T cells
2. Natural killer cells -kill tumor, viraly infected cells, bacterial + protozoa infections -direct contact w infected cells (secrete cytotox
3 classes of Innate immune system molecules 1. PRR (pattern recognition receptors) 2. molecules produced in respond to an infection ( cytokines, antimicrobial peptides, acute phase reactants) 3. complement proteins
pattern recognition receptors are molecules of the innate immune system that recognize (PAMPs) pattern associated molecular patterns how innate system recognizes foregin particles rather than self examples of PAMPS: -DS and SSviral RNA, bacterial flagellin, peptidoglycans and lipotechoid acids on gram pos cell wall, liposaccharides on the gram neg cell wall
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