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Clin Med 208: Psych

Mechanism of tricyclic antidepressants Block norepinephrine and serotonin reuptake in the neuron
Mechanism of SSRIs Block the reuptake of serotonin. Minimal side effects
What type of drug is Cymbalta? SSNRI (blocks 5HT and Norepinephrine)
Mechanism of benzodiazepines Enhance binding and effectiveness of GABA
Most commonly abused benzodiazepine Xanax
Most commonly used benzodiazepine in hospitals Ativan (Lorazepam). Available oral and IV.
Mechanism of antipsychotics Blocks dopamine receptors.
Major Depressive Disorder is diagnosed with 5 or more of these criteria decreased modd, insomnia/hypersomnia, agitation, fatigue, feelings of worthlessness, loss of interest, weight loss, etc.
Depressive disorder with ongoing symptoms that are less in severity lasting greater than 2 years Dysthymic disorder
Patient with history of depressive disorder and then one episode of mania Bipolar Disorder
Distinct period of abnormality and persistent mood lasting at least one week and of sufficient severity to cause impairment in functioning Manic episode
Maintenance meds for Bipolar Disorder Lithiium carbonate and anticonvulsants
Complex disorder that is rooted in abnormalities in the perception and expression of reality. Schizophrenia
Typical course of schizophrenia >6mos, initial psychotic break usually in 20's
Characterized by unrealistic or excessive worry about several life events or activities for a period of at least 6 mos. Generalized Anxiety Disorder
Symptoms of Generalized Anxiety Disorder Muscle tension, easy fatigability, irritability, restlessness, difficulty concentrating
Recurrent episodes of panic attacks, typified by discrete periods of intense fear or discomfort Panic disorder
Intense fear of becoming helpless during a panic attack while in a public place Agoraphobia
Characterized by intrusive thoughts that produce anxiety, by repetitive behaviors aimed at reducing anxiety OCD
Defined by the presence of intrusive recollections related to a specific event that caused feelings of helplessness Post-traumatic Stress Disorder
What percentage of war veterans suffer from PTSD? 30%
What drug is contraindicated for the treatment of PTSD? benzodiazepines (due to abuse potential)
Multiple physical complaints before the age 30 Somatization disorder
Symptoms of somatization disorder include: GI, GU, Pseudocardiac, Pseudoneurologic, sexual dysfunction
Pervasive feeling of ugliness or physical defect based on an overly exaggerated perception of a minor, or absent, physical abnormality Body Dysmorphic Disorder
Loss or alteration in physical functioning during a period of psychological stress Conversion disorder
Preoccupation of having a serious illness based on misinterpretation of physical symptoms that do not respond to physician and clinical reassurance Hypochondriosis
CAGE questions regarding substance abuse. (problem if yes to 2 or more) Feel you should CUT down on drinking? Are you ANNOYED when people criticize you about drinking? Do you ever feel GUILTY? Do you need an EYE-OPENER in the morning?
When does Delirium Tremens occur with alcohol withdrawl? 2-5 days after last drink
What is the number one abused drug? Opiods
Created by: LaurenLofdahl