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Clin Med 206: Derm

Largest organ of the body Skin (16% body weight)
Major organ that controls homeostasis and modulates body temperature/synthesizes vitamin D Skin
3 layers of skin Epidermis, Dermis, Subcutis
Most superficial layer of skin, no blood vessels, forms melanin and keratin Epidermis
Layer of skin that supplies epidermis with nutrients, lots of blood, connective tissue, sweat glands and hair follicles Dermis
Layer of skin that contains adipose tissue/vessels/nerves Subcutis
Change in color of the skin. Flat lesion, <1cm Macule
Macule that is larger than 1 cm referred to as a _______ Plaque
A small <1cm raised lesion with distinct borders. Can be domed, flat-topped or umbilicated. Papule
Large papule Nodule
A raised fluid filled lesion smaller than 1cm Vesicle
A fluid filled lesion greater than 1cm Bullae
An elevated lesion that contains pus (usually infected but can be sterile) Pustule
When in doubt about treatment of skin disease --> under-treat
Best drying agent for weepy skin Water
Ointments are _____ potent than creams MORE (greasier = longer lasting)
Don't treat pregnant women with ________ Retin-A (teratogenic)
#1 dermatologic cause of death Malignant melanoma
Flat brown spots that appear in young children Freckles
Flat brown spots that appear in sun-exposed areas with age Lentigines
Beige/brown/black pigmented lesions that look "stuck on" older patients Seborrheic keratoses
Risk factors for malignant melanoma family hx, fair complexion, sun exposure
4 Types of Malignant Melanoma Nodular, Acral-lentiginous, superficial spreading, lentigo maligna
Very common scaly lesion. Silvery scales on bright red, well-demarcated plaques. Psoriasis
Nail pitting can be seen with _______ Psoriasis
Treatment for generalized psoriasis (>30%) UVB light 3/week, PUVA therapy, Acitretin, Cyclosporine
Pruritic erythema and scaling, excoriation, lichenification (common in kids) Atotpic Dermatitis (Eczema)
Which scaly lesion is much worse in HIV pts? Seborrheic Dermatitis
Fungal infection on trunk, upper arms, neck, face and groin Tinea Versicolor
Malassezia furfur is associated with _______ Tinea Versicolor
Pale patches of skin that are treated with anti-fungal creams Tinea Versicolor
Pre-malignant plaques that can be acquired at tanning salons. Actinic Keratoses
Actinic Keratoses can progress to ________ Squamous cancer (1:1000)
Dermatitis that is usually seen on the faces of children. Treated with antibiotics. Impetigo
Common in puberty. Avoid oily applications. Inflammatory lesions and comedones "black heads" Acne Vulgaris
Flushing, "cauliflower nose", papules over forehead, cheeks and skin. Middle-aged pts. Acne Rosacea
Bacterial. Pustules in hair follicles. May become absess Folliculitis
Superficial fungal infection. Any part of mucous membrane. Whitish curd like substance Candidiasis
Erythematous subcutaneous swelling/papules with red/white halo. Allergic reaction. Urticaria (Hives)
"target lesions" are hallmark of this condition Erythema Multiforme
If mucous membrane is involved in erythema multiforme it can develop into _______. Stevens-Johnson Syndrome
Widespread erythema multiforme, very dangerous, can lead to toxic epidermal necrolysis Stevens-Johnson Syndrome
Pathognomonic of Lyme disease Erythmea Migrans
Infection of cutaneous layer of epidermis Erysipelas
Bullous drug eruptions can be caused by ____ and ____-_ Bactrim and Dilantin/Phenytoin
Warts, corn, seborrheic dermatoses are examples of ________ hyperkeratoses
Commonly in AIDS. Associated with HSV8. Kaposi's Sarcoma
Immunologic inflammation of subcutaneous fat Erythema Nodosum
Erythema Nodosum is most commonly seen with _________ Systemic Lupus
Created by: LaurenLofdahl