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Respiratory stuff
| Question | Answer |
|---|---|
| What does Mac infection stand for and what are the two most common causes | MAC stands for mycobacterium avium complex. The two most common causes are mycobacterium avium and mycobacterium intercellulare |
| What are the classic presentations for MAC | 1. White middle aged male or older n m ale with a history of smoking and underlying chronic obstructive pulmonary disease or 2. Non smoking women over age 50 who has abnormal chest X-ray consistent with bronchiectasis |
| What symptoms will patients have with MAC. | Patients will typically have a cough sometimes with sputum production , usually without fever or weight loss |
| What is the diagnostic criteria for MAC | 1. Imaging studies consistent with pulmonary disease 2. Recurrent isolation of mycobacterium from sputum or isolated from at least one bronchial wash. |
| What could you look for on chest X-ray or CT chest | Will see cavities, multifocal bronchiectasis, and or multiple small nodules |
| What is typical treatment for MAC. | Usually triple therapy is used with a Zithromycin, rifampin and ethambutal, patients will be on antibiotics anywhere from 6 months up to 18 months |
| What are the adverse reactions do you need to watch for when treating for MAC | Azithromycin can prolong Qtc interval Rifampin can cause elevated liver enzymes Ethambutol can cause optic neuritis and color blindness |