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MLT-GTI
Microbiology
Question | Answer |
---|---|
Cause of Diarrhoea? | Villi damage by microorganism & Enterotoxin causes excessive production of cAMP in intestinal cells So, Water remains in the intestine |
Common Pathogens of GTI? | Bacteria: Salmonella, Shigella, Vibrio, Campylobacter, Diarrhoeagenic E.coli Virus: Rotavirus, Norovirus Protozoa: Entamoeba histolytica |
Causes of Salmonella? | Salmonella typhi , Sal. paratyphi A, B & C, causes typhoid fever, life threatening. |
Causes of Shigella? | Bacillary dysentery: invade colonic epithelial cells cell death, damage the large intestine, bloody diarrhoea with mucus |
Causes of Vibrio? | Causes cholera, Cholera toxin (potent enterotoxin, symptoms: abdominal pain, rice watery diarrhoea, Sucrose fermenter yellow colonies on TCBS, GNR curved rods classical biotype highly pathogenic, extinguished, El Tor biotype less pathogenic |
What is Vibrio parahaemolyticus? | Halophilic GNR, Associated with seafood poisoning (GE) Non sucrose fermenter green colonies on TCBS |
What is about campylobacter? | Microaerophilic, GNR spiral or āSā shaped, C. jejuni & C. coli, |