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Background of Pseudomonas aeruginosa? Gram negative rods, non-spore forming Strict aerobe Grow range 5-42C Grow on Blood agar, MacConkey agar, Cetrimide Agar
Biochemical characteristics of Pseudomonas aeruginosa? Catalase test: + Oxidase test: + Motility: + O/F: oxidative Under UV: yellowish green
Why Pseudomonas aeruginosa is resistant to many antibiotics? Multidrug efflux pumps, Chromosomally encoded antibiotic resistance genes ( mexAB , mexXY)
Antibiotics for Pseudomonas aeruginosa? Aminoglycosides (gentamycin) Quinolones (ciprofloxacin) Cephalosporins (ceftazidime)
Background of Campylobacter? Gram negative s-shaped rods Microaerophilic(5-10%) Grow at 42C Grow on Karmali agar, Skirrow's medium, Campy medium
Biochemical characteristics of Campylobacter Oxidase test: + Catalase test: + O/F test: Fermentative
What are the human pathogens of Campylobacter? C. jejuni C. coli Helicobacter pylori
Clinical significance of Helicobacter pylori? Gastric ulcer, peptic ulcer Produce strong Urease to breakdown urea to ammonia, which neutralize gastric acid, helps to gastric colonization
Created by: kencho