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MLT-Pseudo&Campylo
Microbiology
| Question | Answer |
|---|---|
| Background of Pseudomonas aeruginosa? | Gram negative rods, non-spore forming Strict aerobe Grow range 5-42C Grow on Blood agar, MacConkey agar, Cetrimide Agar |
| Biochemical characteristics of Pseudomonas aeruginosa? | Catalase test: + Oxidase test: + Motility: + O/F: oxidative Under UV: yellowish green |
| Why Pseudomonas aeruginosa is resistant to many antibiotics? | Multidrug efflux pumps, Chromosomally encoded antibiotic resistance genes ( mexAB , mexXY) |
| Antibiotics for Pseudomonas aeruginosa? | Aminoglycosides (gentamycin) Quinolones (ciprofloxacin) Cephalosporins (ceftazidime) |
| Background of Campylobacter? | Gram negative s-shaped rods Microaerophilic(5-10%) Grow at 42C Grow on Karmali agar, Skirrow's medium, Campy medium |
| Biochemical characteristics of Campylobacter | Oxidase test: + Catalase test: + O/F test: Fermentative |
| What are the human pathogens of Campylobacter? | C. jejuni C. coli Helicobacter pylori |
| Clinical significance of Helicobacter pylori? | Gastric ulcer, peptic ulcer Produce strong Urease to breakdown urea to ammonia, which neutralize gastric acid, helps to gastric colonization |