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KIN 3600
Lec 25
| Question | Answer |
|---|---|
| Composition of the Alveolar air | does not have the same composition of gases as the atmospheric air |
| Why does composition of gases as the atmospheric air not have the same | -Inhaled air gets mixed with the dead space air - Inhaled air gets mixed with the air that is already in the lungs -Inhaled air gets 100 % humidified -Humidification of the inhaled air adds 4th gas |
| PAO2 | 105 mmHg |
| PACO2 | 40 mmHg |
| PAN2 | 568 mmHg |
| PAH2O | 47 mmHg |
| Total pressure | 760 mmHg |
| Gas exchange in the lungs | ^ pressure to v Pressure |
| Exchange of the respiratory gasses between the alveolar air and pulmonary capillary blood | result of passive diffusion |
| PA | Partial Alveolar pressure |
| Pa | Partial Pressure |
| In the lungs | venous blood is converted to arterial blood |
| In the muscles | arterial blood is converted to venous blood |
| Factors determining the diffusion rate of respiratory gases across the respiratory membrane | -Difference of partial pressure across the membrane (ΔP) -Thickness of the membrane (T) -Surface area of the active respiratory membrane (A) -Solubility of gasses in water (S) -Square root of the molecular weight (√ MW) -Temperature (T°) |
| Difference of partial pressure across the membrane (ΔP) | - ^pressure difference = faster diffusion -Directly Proportional |
| Thickness of the membrane (T) | -Thicker membrane = Slow diffusion -Thinner membrane = Faster diffusion -Inverse proportional |
| Surface area of the active respiratory membrane (A) | - ^ respiratory membrane SA = ^ faster diffusion - Directly proportional |
| Solubility of gasses in water (S) | - ^Solubility = faster diffusion - Directly Proportional - CO2 ^ higher solubility |
| Square root of the molecular weight (√ MW) | - ^ heavier gas = slower diffusion - Inverse proportional |
| Temperature (T°) | - ^ temp = ^ faster diffusion - Directly Proportional |
| Diffusion rate is directly proportional | ΔP, A, S, T° |
| Diffusion rate is inversely proportional | T, √ MW |
| O2 transport in blood Dissolved in plasma water | 1 % |
| O2 transport in blood As Oxyhemoglobin in RBC | 99 % (1.34 ml O2/g Hb) |
| Hb increases the O2 carrying capacity of blood | by approximately 65 times |
| Blood Hb concentration men | 15% |
| Blood Hb concentration women | 13.5% |
| Anemia | Decreased # of RBC or lower than normal Hb content of each RBC |
| What does anemia do? | Reduction in endurance performance because there is already a small about of O2 supplied so it affects aerobic performance |
| Does anemia affect sprint performance? | may not be affected only acute blood loss Depends on anaerobic E.T. not aerobic |
| Oxyhemoglobin | O2 attached to Hemoglobin (Hb) |
| Deoxyhemoglobin | No O2 attach to Hb |
| Curve can shift R, why? | - Effect of pH (Bohr Effect) - Effect of Temperature - Effect of 2,3 BPG levels in RBC - Effect of Pco2 |
| Myoglobin Dissociation Curve | - Binds O2 does not let go – strong - Higher affinity for O2 - In muscle, hemo: RCB - Shift more left on curve (75%) |
| Deep sea diving affects | - Nitrogen narcosis - Oxygen poisoning - Effect on PO2 of plasma water - Gas mixture of diving |
| Nitrogen narcosis | -Pressure so high. They get confused & end up dying -N2 forced into blood and joint cartilage -Causes pain -Bubbles in blood (heart attack) |
| Oxygen poisoning | -Partial pressure ^ -Break DNA |
| Gas mixture of diving | o Tanks 99% He o 1% O2 - non narcotic affect |
Created by:
rmart11
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