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Hormones
Hormones and their functions
| Source Gland | Target(s) | Effects(s) on Target(s) | ||
|---|---|---|---|---|
| Insulin | ~~~ | Pancreas | Body Cells | Decreases blood glucose; Converts glucose to glycogen or fat for storage. |
| Glucagon | ~~~ | Pancreas | Liver | Breaks down glycogen to glucose to increase blood glucose. |
| Calcitonin | ~~~ | Thyroid gland | Bones | Decrease blood calcium; Mineral deposition. |
| Parathyroid Hormone | PTH | Parathyroid glands | Bones; Kidneys | Increases blood calcium; Mineral resorption; Stimulates kidneys to convert vitamin D to the active form, calcitriol. |
| Growth Hormone releasing hormone | GHRH | Hypothalamus | Anterior Pituitary | Stimulates anterior pituitary to secrete GH. |
| Growth Hormone | GH | Anterior Pituitary | Skeletal muscles and long bones | Growth of skeletal muscle and long bones |
| Thyrotropin releasing hormone | TRH | Hypothalamus | Anterior Pituitary | Stimulates anterior pituitary to secrete PRL. |
| Prolactin releasing hormone | PRH | Hypthalamus | Anterior Pituitary | Stimulates anterior pituitary to secrete PRL. |
| Prolactin | PRL | Anterior Pituitary | Secretory cells of mammary glands | Milk synthesis |
| Thyrotropin releasing hormone | TRH | Hypothalamus | Anterior Pituitary | Stimulates anterior pituitary to secrete TSH. |
| Thyroid stimulating hormone | TSH | Anterior Pituitary | Thyroid gland | Stimulates thyroid to secrete TH. |
| Thyroid hormone | TH (T3, T4) | Thyroid gland | Body Cells | Increase basal metabolic rate. |
| Corticotropin releasing hormone | CRH | Hypothalamus | Anterior Pituitary | Stimulates anterior pituitary to secrete ACTH. |
| Adenocorticotropic Hormone | ACTH | Anterior Pituitary | Adrenal Cortex | Stimulates adrenal cortex to secrete mineralocorticoids. |
| Mineralocorticoids | ~~~ | Adrenal cortex | Distal tubules and collecting ducts of kidneys | Sodium and water reabsorption; Potassium secretion. |
| Corticotropin Releasing Hormone | CRH | Hypothalamus | Anterior pituitary | Stimulates anterior pituitary to secrete ACTH. |
| Adenocorticotropic Hormone | ACTH | Anterior pituitary | Adrenal cortex | Stimulates adrenal cortex to secrete glucocorticoids. |
| Glucocorticoids | ~~~ | Adrenal cortex | Body cells | Anti-inflammatory; Increases blood glucose. |
| Corticotropin releasing hormone | CRH | Hypothalamus | Anterior pituitary | Stimulates anterior pituitary to secrete ACTH. |
| Adenocorticotropic Hormone | ACTH | Anterior pituitary | Adrenal cortex | Stimulates adrenal cortex to secrete gonadocorticoids. |
| Gonadocorticoids | ~~~ | Adrenal cortex | Body cells | Similar to estrogens and testosterone; Insignificant amounts produced with minimal effects. |
| Gonadotropin releasing hormone | GnRH | Hypothalamus | Anterior pituitary | Stimulates anterior pituitary to release FSH and LH. |
| Estrogens | ~~~ | Ovaries | Body cells | Regrowth of functional layer in endometrium of uterus after menstruation; Growth of lactiferous ducts/sinuses in mammary glands; Development of secondary sex characteristics; Maintains pregnancy. |
| Follicle stimulating hormone and Lutenizing hormone. | FSH & LH | Anterior pituitary | Ovaries | Simulate follicles in ovaries to cause oogenesis, ovulation, and secretion of estrogens. |
| Gonadotropin releasing hormone | GnRH | Hypothalamus | Anterior pituitary | Stimulates anterior pituitary to release FSH and LH. |
| Follicle stimulating hormone and Lutenizing hormone | FSH & LH | Anterior pituitary | Testes | FSH: Stimulates nurse cells in testes to secrete androgen-binding protein (ABP) and inhibin. LH: Stimulates interstitial endocrine cells in testes to secrete testosterone. |
| Testosterone | ~~~ | Testes | Body Cells | Sexual maturation; Spermatogenesis; Development of secondary sex characteristics. |
| Antidiurectic Hormone | ADH | Synthesized by: Hypothalamus Secreted by: Posterior Pituitary | Distal tubules and collecting ducts of kidneys | Water reabsorption |
| Oxytocin | ~~~ | Synthesized by: Hypthalamus Secreted by: Posterior Pituitary | Uterus; Myoepithelial cells of mammary glands | Uterine contractions during labor and coitus; milk ejection. |