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KIN 3600

Lec 18

Osteotendinal junction bone & tendon junction
Myotendinal Junction muscle & tendon junction
Tendons fusion of all 3 C.T. together @ the 2 distal ends of the muscle forms tendons which becomes continuous with periosteum
Sarcolemma (plasmalemma) -Phospholipid bilayer with imbedded proteins -Thickness 7.5 nm -Highly folded
Sarcosol Liquid portion of cell/plasma
Sarcoplasm Whatever is inside membrane Sarcolemme+sarcosol=sacoplasma
Myofibrils -Longitudinal, vertical densely packed individual fibers -Diameter: 1-3mm
I-band -Isotropic -Light & uniform
A-band -Anisotropic -Dark & dense
Sarcomere -Located between two adjacent z-discs -Contractile unit of myofibrils -Series arrangement & parallel arrangement
Series arrangement ^ range & velocity of contraction
parallel arrangement ^ Force of contraction
H-zone Hellerscheibe (German) Middle of A-band
M-line -Mittelscheibe -Middle H-zone
Z disc Center of each I-band
Thick filament -Myosin protein -Organized antiparallel (HEADS ON BOTH SIDES) (Tails twist together ) -Heads contain ATP & Actin -Chemical energy is immediately converted to mechanical energy (Moves myosin head)
Thin filament Actin - contractile protein G-actin -Globular protein attach to each other (beads) F-actin - G-actin side by side (necklace)
Troponin I binds to actin
Troponin T Binds to tropomyosin
Troponin C Binds to calcium
Thick & thin filaments interdigitate in a hexagonal array 1 Thick: 6 Thin
Mechanism of muscular contraction Thin pulled/slides over thick filaments
What happens to I-band during muscle fiber shortening? narrows & disappears
What happens to A-band during muscle fiber shortening? remains the same length
What happens to H-zone during muscle fiber shortening? narrows, disappears, reappears darker color because of over lapping & becomes a wider zone
Created by: rmart11