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Enterobacteriaceae 1

Eschericia species

Aspect of EschericiaInformation
Characteristics of Eschericia coli (Main Pathogen) Falls between Opportunistic & Overt Pathogen / Normal bowel inhabitant (coliform) / Some strains (produced in other animals) produce toxins that can cause serious GI infections
Clinical Signifigance UTIs, Diarrheal disease, Sepsis, Neonatal meningitis / can cause meningitis & bacteremia in immunocompromised PTs
E.coli as an Opportunistic pathogen Individuals who are debilitated or have other predisposing factors are at much higher risk for infection than healthy persons
Urinary Tract Infections E. coli is an extremely common UTI in: women, toddlers in diapers, hospitalized patients w indwelling catheters / infection usually caused by fecal contamination / Organism may affect any part of the urinary tract, including the kidneys (pyelonephritis)
Diarrheal Infections E. coli that cause diarrhea are classified according to certain virulence factors that result in different mechanisms of disease productions
Enteropathogenic E.coli (EPEC) Diarrhea in infants in low income nations / Organism attaches to mucous cells of the small bowel
Enterotoxigenic E.coli (ETEC) - "Traveler's diarrhea" Profuse, watery, stools / transmitted by contaminated food & water / enterotoxins mediate secretion of water & electrolytes into the bowel
Enteroinvasive E.coli (EIEC) - Dysentery Usually in young children living in unsanitary conditions / organism invades enterocytes lining the large intestine
Enterohemorrhagic E.coli (EHEC) - "Hemorrhagic E.coli" Causes bleeding of the mucosal of the intestinal lining / transmitted by undercooked ground beef or raw milk / toxin produced that increases virulence in certain serotypes including E.coli 0157:H7
Enteroaggregative E.coli (EAEC) causes prolonged watery diarrhea, pathogenic mechanism is unknown
Created by: nbechen3
 

 



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