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Leukocyte Unit
Leukocyte Development Stages: Granulocytes, Monocytes, Lymphocytes
| Term | Definition |
|---|---|
| Myeloblast | Size: 10-18μm Nucleus: Large; oval Chromatin: Finely reticular Nucleoli: 1-5 present; light staining Cytoplasm: Small rim of basophilic stippling No granules present |
| Promyelocyte | Size: 14-20μm Nucleus: Difficult to see Chromatin: More condensed Nucleoli: Present Cytoplasm: Pale blue gray; moderate in amount, Azurophillic granules, very prominent |
| Myelocyte | Size: 12-18μm Nucleus: Oval shaped; smaller Chromatin: Clumped chromatin Nucleoli: None present Cytoplasm: Somewhat blue |
| Metamyelocyte | Size: 10-18μm Nucleus: Becoming kidney bean shape ChromatinL Dense or clumped Nucleoli: None present Cytoplasm: Specific granulation of type is apparent |
| Band | Size: 10-18μm Nucleus: Elongated nucleus, no pinching Cytoplasm: Specific granulation of type is apparent; |
| Segmented Neutrophil | Size: 10-18μm Nucleus: 3-5 lobes, held together by thin filaments; purple/blue Cytoplasm: Azure (Purple/pink/blue) granules |
| Segmented Eosinophil | Size: 10-18μm Nucleus: Typically bi-lobed (up to 3, fuller) purple blue Cytoplasm: Pink/orange/red granules, Large crystalline/shiny, mainly in cytoplasm |
| Segmented Basophil | Size: 10-18μm Nucleus: 3-5 lobes; purple blue, difficult to see Cytoplasm: Purple/blue/black granules, variable in size, throughout cytoplasm |
| Monoblast | Size: 12-20μm Nucleus: Round/oval, central or eccentric, folding; large Chromatin:Fine, lightly dispersed chromatin Nucleoli: 1-4 visible Cytoplasm: Basophilic, intensely stained periphery, prominent perinuclear zone; moderate in amount, No granules |
| Promonocyte | Size: 12-20μm Nucleus: Oval, indented, light purple; large Chromatin: Fine and spongy pattern Nucleoli: 1-5 visible Cytoplasm: Gray blue w Fine dust like azurophilic (red-purple) granules |
| Monocyte | Size: 14-20μm Nucleus: Round, kidney shaped, can be indented or 2+ lobes Chromatin:Lacey chromatin pattern Nucleoli: None present Cytoplasm: Blue gray Fine granulation (ground glass), vaculoes may also be present |
| Lymphoblast | Size: 15-20μm Nucleus: Round/oval, moderate Chromatin: Delicate chromatin pattern Nucleoli: 1-2 present Cytoplasm: Medium blue w dark blue border, abundant; No granules |
| Prolymphocyte | Size: 15-18μm Nucleus: Round/oval, large Chromatin: Slightly condensed chromatin pattern Nucleoli: 0-1 present Cytoplasm: Medium blue with thin darker blue rim, reduced; Azo granules may be present |
| Lymphocyte | Size: 17-20μm Nucleus:Round/oval, cleft may be present, large Chromatin: Dense clumped chromatin pattern Nucleoli: None present Cytoplasm: Light sky blue, scant in volume; a few azo-granules may be present |